Gender‐specific differences in major cardiac events and mortality in lamin A/C mutation carriers
IAW van Rijsingen, EA Nannenberg… - European journal of …, 2013 - Wiley Online Library
Aims Mutations in the lamin A/C gene (LMNA) cause a variety of clinical phenotypes,
including dilated cardiomyopathy. LMNA is one of the most prevalent mutated genes in …
including dilated cardiomyopathy. LMNA is one of the most prevalent mutated genes in …
Clinical manifestations and long-term mortality in lamin A/C mutation carriers from a Japanese Multicenter Registry
K Nakajima, T Aiba, T Makiyama, S Nishiuchi… - Circulation …, 2018 - jstage.jst.go.jp
Background: Mutation in the lamin A/C gene (LMNA) is associated with several cardiac
phenotypes, such as cardiac conduction disorders (CCD), atrial arrhythmia (AA), malignant …
phenotypes, such as cardiac conduction disorders (CCD), atrial arrhythmia (AA), malignant …
Gene-Based Risk Stratification for Cardiac Disorders in LMNA Mutation Carriers
S Nishiuchi, T Makiyama, T Aiba… - Circulation …, 2017 - Am Heart Assoc
Background—Mutations in LMNA (lamin A/C), which encodes lamin A and C, typically cause
age-dependent cardiac phenotypes, including dilated cardiomyopathy, cardiac conduction …
age-dependent cardiac phenotypes, including dilated cardiomyopathy, cardiac conduction …
Meta-analysis of clinical characteristics of 299 carriers of LMNA gene mutations: do lamin A/C mutations portend a high risk of sudden death?
JH Van Berlo, WG De Voogt, AJ Van Der Kooi… - Journal of molecular …, 2005 - Springer
This study evaluated common clinical characteristics of patients with lamin A/C gene
mutations that cause either isolated dilated cardiomyopathy or dilated cardiomyopathy in …
mutations that cause either isolated dilated cardiomyopathy or dilated cardiomyopathy in …
Long-term arrhythmic and nonarrhythmic outcomes of lamin A/C mutation carriers
S Kumar, SH Baldinger, E Gandjbakhch… - Journal of the American …, 2016 - jacc.org
Background: Mutations in LMNA are variably expressed and may cause cardiomyopathy,
atrioventricular block (AVB), or atrial arrhythmias (AAs) and ventricular arrhythmias (VA) …
atrioventricular block (AVB), or atrial arrhythmias (AAs) and ventricular arrhythmias (VA) …
Lamin A/C cardiomyopathy: young onset, high penetrance, and frequent need for heart transplantation
NE Hasselberg, TF Haland, J Saberniak… - European heart …, 2018 - academic.oup.com
Abstract Aims Lamin A/C (LMNA) mutations cause familial dilated cardiomyopathy (DCM)
with frequent conduction blocks and arrhythmias. We explored the prevalence, cardiac …
with frequent conduction blocks and arrhythmias. We explored the prevalence, cardiac …
Risk predictors in a Spanish cohort with cardiac laminopathies. The REDLAMINA registry
R Barriales-Villa, JP Ochoa… - Revista Española de …, 2021 - Elsevier
Introduction and objectives According to sudden cardiac death guidelines, an implantable
cardioverter-defibrillator (ICD) should be considered in patients with LMNA-related dilated …
cardioverter-defibrillator (ICD) should be considered in patients with LMNA-related dilated …
Natural history of dilated cardiomyopathy due to lamin A/C gene mutations
MRG Taylor, PR Fain, G Sinagra, ML Robinson… - Journal of the American …, 2003 - jacc.org
Objectives: We examined the prevalence, genotype-phenotype correlation, and natural
history of lamin A/C gene (LMNA) mutations in subjects with dilated cardiomyopathy (DCM) …
history of lamin A/C gene (LMNA) mutations in subjects with dilated cardiomyopathy (DCM) …
Clinical disease presentation and ECG characteristics of LMNA mutation carriers
L Ollila, K Nikus, M Holmström, M Jalanko… - Open …, 2017 - openheart.bmj.com
Objective Mutations in the LMNA gene encoding lamins A and C of the nuclear lamina are a
frequent cause of cardiomyopathy accounting for 5–8% of familial dilated cardiomyopathy …
frequent cause of cardiomyopathy accounting for 5–8% of familial dilated cardiomyopathy …
Risk factors for malignant ventricular arrhythmias in lamin A/C mutation carriers: a European cohort study
IAW van Rijsingen, E Arbustini, PM Elliott… - Journal of the American …, 2012 - jacc.org
Objectives: The purpose of this study was to determine risk factors that predict malignant
ventricular arrhythmias (MVA) in Lamin A/C (LMNA) mutation carriers. Background: LMNA …
ventricular arrhythmias (MVA) in Lamin A/C (LMNA) mutation carriers. Background: LMNA …