Introduction: The objective of this guideline is to outline the appropriate use of
methylprednisolone sodium succinate (MPSS) in patients with acute spinal cord injury (SCI) …

Study Design: Systematic review and meta-analysis. Objective: The objective of this study
was to conduct a systematic review to assess the comparative effectiveness and safety of …

Objectives. Randomized trials are widely recognized as providing the most reliable
evidence for assessing efficacy and safety of therapeutic interventions. This evidence base …

BACKGROUND CONTEXT: Methylprednisolone has evolved during the 1990s, through the
results obtained from the National Acute Spinal Cord Injury Studies NASCIS II and III, as a …

Study Design. Retrospective single-center study. Objective. To evaluate the recovery of
motor function and the early complications in patients with acute cervical spinal cord injury …

Study design: Systematic literature review for primary data using predefined inclusion,
exclusion and validity criteria. Primary outcome measure was standardised neurological …

Object. Since publication in 1990, results from the National Acute Spinal Cord Injury Study II
(NASCIS II) trial have changed the way patients suffering an acute spinal cord injury (SCI) …

Background: A systematic review of the evidence pertaining to methylprednisolone infusion
following acute spinal cord injury was conducted in order to address the persistent confusion …

© 2003 Canadian Medical Association or its licensors tant functional gain, especially for
patients with cervical spinal cord injuries. Therefore, even the small improvement observed …

In prior analyses of the effectiveness of methylprednisolone for the treatment of patients with
acute traumatic spinal cord injuries (TSCIs), the prognostic importance of patients' …