Roles of inflammation, oxidative stress, and vascular dysfunction in hypertension

QN Dinh, GR Drummond, CG Sobey… - BioMed research …, 2014 - Wiley Online Library
Hypertension is a complex condition and is the most common cardiovascular risk factor,
contributing to widespread morbidity and mortality. Approximately 90% of hypertension …

Is hypertension an inflammatory disease?

JJ Li, CH Fang, RT Hui - Medical hypotheses, 2005 - Elsevier
Hypertension has been recognized as a multi-factorial trait resulting from the effect of a
combination of environmental and genetic factors, including excess dietary salt or alcohol …

Inflammation in hypertension

C Savoia, EL Schiffrin - Current opinion in nephrology and …, 2006 - journals.lww.com
Inflammatory processes are important participants in the pathophysiology of hypertension
and cardiovascular disease. The identification of the mechanisms leading to the activation of …

Inflammation, immunity, and oxidative stress in hypertension—partners in crime?

IR Barrows, A Ramezani, DS Raj - Advances in chronic kidney disease, 2019 - Elsevier
Hypertension is considered as the most common risk factor for cardiovascular disease.
Inflammatory processes link hypertension and cardiovascular disease, and participate in …

Role of inflammation, immunity, and oxidative stress in hypertension: New insights and potential therapeutic targets

Z Zhang, L Zhao, X Zhou, X Meng, X Zhou - Frontiers in immunology, 2023 - frontiersin.org
Hypertension is regarded as the most prominent risk factor for cardiovascular diseases,
which have become a primary cause of death, and recent research has demonstrated that …

Molecular and cellular mechanisms in vascular injury in hypertension: role of angiotensin II–editorial review

RM Touyz - Current opinion in nephrology and hypertension, 2005 - journals.lww.com
Inflammation, oxidative stress and hypertension are closely interrelated. Here we discuss
the (patho) physiology of vascular inflammation in hypertension, focusing specifically on the …

Inflammation may be a bridge connecting hypertension and atherosclerosis

JJ Li, JL Chen - Medical hypotheses, 2005 - Elsevier
Pathogenesis of the atherosclerotic process is deemed as multi-factorial, and characterized
by chronic inflammatory response. Although hypertension is known to be one of the most …

Vascular inflammation: a role in vascular disease in hypertension?

A Virdis, EL Schiffrin - Current opinion in nephrology and …, 2003 - journals.lww.com
Inflammatory mechanisms are important participants in the pathophysiology of hypertension
and cardiovascular disease. The identification of useful markers of inflammation, of new …

Oxidative stress and endothelial dysfunction in hypertension

E Schulz, T Gori, T Münzel - Hypertension Research, 2011 - nature.com
Systemic arterial hypertension is a highly prevalent cardiovascular risk factor that causes
significant morbidity and mortality, and is becoming an increasingly common health problem …

Inflammation in hypertension

L Xiao, DG Harrison - Canadian Journal of Cardiology, 2020 - Elsevier
For more than 50 years, evidence has accumulated that inflammation contributes to the
pathogenesis of hypertension. Immune cells have been observed in vessels and kidneys of …