Resveratrol prevents age-related memory and mood dysfunction with increased hippocampal neurogenesis and microvasculature and reduced glial activation

M Kodali, VK Parihar, B Hattiangady, V Mishra… - Scientific reports, 2015 - nature.com
Greatly waned neurogenesis, diminished microvasculature, astrocyte hypertrophy and
activated microglia are among the most conspicuous structural changes in the aged …

Resveratrol: a potential hippocampal plasticity enhancer

GP Dias, G Cocks… - Oxidative medicine …, 2016 - Wiley Online Library
The search for molecules capable of restoring altered hippocampal plasticity in psychiatric
and neurological conditions is one of the most important tasks of modern neuroscience. It is …

Effects of resveratrol on memory performance, hippocampal functional connectivity, and glucose metabolism in healthy older adults

AV Witte, L Kerti, DS Margulies… - Journal of Neuroscience, 2014 - Soc Neuroscience
Dietary habits such as caloric restriction or nutrients that mimic these effects may exert
beneficial effects on brain aging. The plant-derived polyphenol resveratrol has been shown …

Resveratrol preserves cerebrovascular density and cognitive function in aging mice

CA Oomen, E Farkas, V Roman… - Frontiers in aging …, 2009 - frontiersin.org
Resveratrol, a natural polyphenol abundant in grapes and red wine, has been reported to
exert numerous beneficial health effects. Among others, acute neuroprotective effects of …

Resveratrol enhances neuroplastic changes, including hippocampal neurogenesis, and memory in Balb/C mice at six months of age

M Torres-Pérez, RI Tellez-Ballesteros, L Ortiz-López… - PloS one, 2015 - journals.plos.org
Resveratrol (RVTL) is a flavonoid found in red wine and has been publicized heavily as an
anti-aging compound. Indeed, basic research confirms that although there is much hype in …

Effects of resveratrol on memory performance, hippocampus connectivity and microstructure in older adults–A randomized controlled trial

S Huhn, F Beyer, R Zhang, L Lampe, J Grothe… - Neuroimage, 2018 - Elsevier
Introduction The polyphenol resveratrol has been suggested to exert beneficial effects on
memory and the aging hippocampus due to calorie-restriction mimicking effects. However …

Chronic administration of resveratrol prevents morphological changes in prefrontal cortex and hippocampus of aged rats

E Monserrat Hernández‐Hernández… - Synapse, 2016 - Wiley Online Library
Resveratrol may induce its neuroprotective effects by reducing oxidative damage and
chronic inflammation apart from improving vascular function and activating longevity genes …

Effects of pterostilbene and resveratrol on brain and behavior

SM Poulose, N Thangthaeng, MG Miller… - Neurochemistry …, 2015 - Elsevier
Age is the greatest universal risk factor for neurodegenerative diseases. During aging, these
conditions progress from minor loss of function to major disruptions in daily life, loss of …

Resveratrol attenuates peripheral and brain inflammation and reduces ischemic brain injury in aged female mice

S Im Jeong, JA Shin, S Cho, HW Kim, JY Lee… - Neurobiology of …, 2016 - Elsevier
Resveratrol is known to improve metabolic dysfunction associated with obesity. Visceral
obesity is a sign of aging and is considered a risk factor for ischemic stroke. In this study, we …

Differential responses of Trans-Resveratrol on proliferation of neural progenitor cells and aged rat hippocampal neurogenesis

V Kumar, A Pandey, S Jahan, RK Shukla, D Kumar… - Scientific reports, 2016 - nature.com
The plethora of literature has supported the potential benefits of Resveratrol (RV) as a life-
extending as well as an anticancer compound. However, these two functional discrepancies …