Association of the PD‐1.3A allele of the PDCD1 gene in patients with rheumatoid arthritis negative for rheumatoid factor and the shared epitope

L Prokunina, L Padyukov, A Bennet… - … : Official Journal of …, 2004 - Wiley Online Library
Objective To study the frequency of allele A of polymorphism PD‐1.3 of the PDCD1 gene in
patients with rheumatoid arthritis (RA) and its subsets, based on the presence of rheumatoid …

A new haplotype of PDCD1 is associated with rheumatoid arthritis in Hong Kong Chinese

EKP Kong, L Prokunina‐Olsson… - Arthritis & …, 2005 - Wiley Online Library
Objective The programmed death 1 (PD‐1) molecule is a negative regulator of T cells, and a
genetic association between PD‐1 and systemic lupus erythematosus and rheumatoid …

Association of PDCD1 with susceptibility to systemic lupus erythematosus: evidence of population‐specific effects

I Ferreiros‐Vidal, JJ Gomez‐Reino… - … : Official Journal of …, 2004 - Wiley Online Library
Objective The A allele of the PD1. 3 single‐nucleotide polymorphism (SNP) on the
programmed cell death gene PDCD1 was markedly more frequent in patients with systemic …

Association of a PDCD1 polymorphism with renal manifestations in systemic lupus erythematosus

M Johansson, L Ärlestig, B Möller… - Arthritis & …, 2005 - Wiley Online Library
Objective To analyze the association of the PD‐1.3 polymorphism within the PDCD1 gene in
patients with systemic lupus erythematosus (SLE) from the homogeneous population in …

[引用][C] The systemic lupus erythematosus–associated PDCD1 polymorphism PD1.3A in lupus nephritis

L Prokunina, I Gunnarsson, G Sturfelt… - … : Official Journal of …, 2004 - Wiley Online Library
Systemic lupus erythematosus (SLE) is an autoimmune inflammatory disease with a
prevalence of 0.05–0.07% in women of European descent (1). Chronic inflammation in …

Association of PDCD1 genetic variation with risk and clinical manifestations of systemic lupus erythematosus in a multiethnic cohort

CM Thorburn, L Prokunina-Olsson, KA Sterba… - Genes & …, 2007 - nature.com
We evaluated the roles of five single-nucleotide polymorphisms (SNPs) within PDCD1, and
haplotypes defined by these SNPs, for the development of systemic lupus erythematosus …

Role of an intronic polymorphism in the PDCD1 gene with the risk of sporadic systemic lupus erythematosus and the occurrence of antiphospholipid antibodies

DK Sanghera, S Manzi, F Bontempo, C Nestlerode… - Human genetics, 2004 - Springer
Recently, a polymorphism in intron 4 (G/A) of the programmed cell death 1 (PDCD1) gene
was shown to be associated with systemic lupus erythematosus (SLE) risk in familial and …

A Promoter Region Polymorphism in PDCD-1 Gene Is Associated with Risk of Rheumatoid Arthritis in the Han Chinese Population of Southeastern China

CP Liu, JA Jiang, L Gao, XH Hu… - … journal of genomics, 2014 - Wiley Online Library
Objective. Programmed cell death 1 (PD‐1) induces negative signals to T cells during
interaction with its ligands and is therefore a candidate gene in the development of …

[HTML][HTML] Association of the programmed cell death 1 (PDCD1) gene polymorphism with ankylosing spondylitis in the Korean population

SH Lee, YA Lee, DH Woo, R Song, EK Park… - Arthritis research & …, 2006 - Springer
Abstract The PD-1 (programmed death 1) molecule is a negative regulator of T cells. PDCD1
(programmed cell death 1) has been reported to have a genetic association in systemic …

[HTML][HTML] Association of PDCD1 polymorphisms with childhood-onset systemic lupus erythematosus

R Velázquez-Cruz, L Orozco… - European journal of …, 2007 - nature.com
A regulatory single nucleotide polymorphism (SNP) PD1. 3G/A located on programmed cell
death 1 (PDCD1) gene, was shown to be involved in susceptibility to systemic lupus …