Assembly formation is stabilized by Parvalbumin neurons and accelerated by Somatostatin neurons

F Lagzi, MC Bustos, AM Oswald, B Doiron - BioRxiv, 2021 - biorxiv.org
Learning entails preserving the features of the external world in the neuronal
representations of the brain, and manifests itself in the form of strengthened interactions …

[HTML][HTML] Purely STDP-based assembly dynamics: Stability, learning, overlaps, drift and aging

P Manz, RM Memmesheimer - PLOS Computational Biology, 2023 - journals.plos.org
Memories may be encoded in the brain via strongly interconnected groups of neurons,
called assemblies. The concept of Hebbian plasticity suggests that these assemblies are …

Interacting synapses stabilise both learning and neuronal dynamics in biological networks

EJ Agnes, TP Vogels - BioRxiv, 2021 - biorxiv.org
Distinct synapses influence one another when they undergo changes, with unclear
consequences for neuronal dynamics and function. Here we show that synapses can …

Training and spontaneous reinforcement of neuronal assemblies by spike timing

GK Ocker, B Doiron - arXiv preprint arXiv:1608.00064, 2016 - arxiv.org
The synaptic connectivity of cortex is plastic, with experience shaping the ongoing
interactions between neurons. Theoretical studies of spike timing-dependent plasticity …

[HTML][HTML] Learning excitatory-inhibitory neuronal assemblies in recurrent networks

O Mackwood, LB Naumann, H Sprekeler - Elife, 2021 - elifesciences.org
Understanding the connectivity observed in the brain and how it emerges from local
plasticity rules is a grand challenge in modern neuroscience. In the primary visual cortex …

[HTML][HTML] Managing neuronal ensembles: somatostatin interneuron subpopulations shape and protect cortical neuronal ensembles for learning

M Serrano, P Caroni - Neuron, 2019 - cell.com
Learning is accompanied by temporal compression and sharpening of neuronal firing
sequences. In this issue of Neuron, Adler et al.(2019), using a motor skill paradigm and its …

Long-term plasticity induces sparse and specific synaptic changes in a biophysically detailed cortical model

A Ecker, DE Santander, M Abdellah, JB Alonso… - bioRxiv, 2023 - biorxiv.org
Synaptic plasticity underlies the brain's ability to learn and adapt. This process is often
studied in small groups of neurons in vitro or indirectly through its effects on behavior in vivo …

Interplay between homeostatic synaptic scaling and homeostatic structural plasticity maintains the robust firing rate of neural networks

H Lu, S Diaz, M Lenz, A Vlachos - bioRxiv, 2023 - biorxiv.org
Critical network states and neural plasticity are essential for flexible behavior in an ever-
changing environment, which allows for efficient information processing and experience …

Regulation of parvalbumin interneuron plasticity by neuropeptide-encoding genes

M Selten, C Bernard, F Hamid, A Hanusz-Godoy… - bioRxiv, 2023 - biorxiv.org
Neuronal activity is regulated in a narrow permissive band for the proper operation of neural
networks. Changes in synaptic connectivity and network activity, for example, during …

Dendritic growth and synaptic organization from activity-independent cues and local activity-dependent plasticity

JH Kirchner, L Euler, J Gjorgjieva - bioRxiv, 2022 - biorxiv.org
Dendritic branching and synaptic organization shape single neuron and network
computations. How they emerge simultaneously during brain development as neurons …