Interleukin-6 (IL-6) is a multifunctional cytokine that is proving to be a major contributor to the
acute phase inflammatory response. IL-6 expression is normally low and serum levels are …

Summary Interleukin-6 (IL-6) is a pro-inflammatory cytokine with a wide range of functions.
Perhaps the most important physiologically is its role as a mediator of the acute phase …

Investigators have reported an increase, decrease, or no effect of age on interleukin-6 (IL-6)
production. Differences in experimental conditions and the health status of subjects may …

Interleukin-6 (IL-6) is a proinflammatory cytokine that is normally tightly regulated and
expressed at low levels, except during infection, trauma, or other stress. Among several …

Interleukin‐6 (IL‐6) is a multifunctional cytokine that presumably plays its major role as a
mediator of several of the acute phase inflammatory responses. These include inflammatory …

Interleukin-2 (IL-2) is a growth promoting cytokine that has received a great deal of attention
over the past decade with respect to aging and cancer. It is produced primarily by helper T …

The decrease in T-cell proliferation with age is due, in part, to the decline in the production of
IL-2. Since IL-1 is needed to trigger IL-2 production, we determined the IL-1 producing …

Spleen and lymph node cells from young (3 to 4 months) and old (24 to 36 months) mice of
two inbred lines and one hybrid stock were assessed for the effect of age on IL 2 production …

The human interleukin IL-6 was originally cloned in 1986. In 1993, William Ershler, in his
article “IL-6: A Cytokine for Gerontologists,” indicated IL-6 as one of the main signaling …

The age of an individual is an important, independent risk factor for many of the most
common diseases afflicting modern societies. Interleukin‐7 (IL‐7) plays a central, critical role …