Drug hypersensitivity reactions (DHRs) are uncommon but potentially fatal adverse events.
Their diagnosis and prediction are difficult given their variable presentation and the overlap …

The term drug hypersensitivity refers to a category of adverse drug reactions mediated by
various immunological and nonimmunological mechanisms. Small-molecule drugs and …

Adverse drug reactions are a difficult problem faced by clinicians in everyday practice. The
mechanisms of drug hypersensitivity are not well understood. This is reflected by difficulties …

This special issue on biomarkers in drug hypersensitivity consists of 11 articles focusing on
recent advancements related to this exciting field. Biomarkers, especially those based on …

Drug hypersensitivity reactions (DHRs) are a type of adverse drug reaction that can occur
with different classes of drugs and affect multiple organ systems and patient populations …

Drug hypersensitivity reactions (DHRs) represent a global threat to healthcare systems due
to their incidence, with a significant increase over last years1. DHR figures are …

Adverse drug reactions (ADRs) are defined as any noxious and unintended response to a
drug. ADRs may be predictable, based on known pharmacologic properties of a drug, or …

Background For most physicians, quantification of drug-specific immunoglobulin E (drug-
sIgE) antibodies constitutes the primary in vitro measure to document immediate drug …

Severe delayed drug hypersensitivity reactions comprise different clinical entities and can
involve different immune-mediated mechanisms. Common examples are severe cutaneous …

Drug hypersensitivity reactions (DHRs) are typically classified into immediate and delayed
reactions based on the time interval between drug exposure and onset of symptoms. Clinical …