Background Rett syndrome (RTT) is a pervasive developmental disorder that is progressive
and has no effective cure. Immune dysregulation, oxidative stress, and excess glutamate in …

After publication of the article [1], it has been brought to our attention that an author's name
has been formatted incorrectly. The correct name should be “Rangaramanujam M. Kannan” …

Rett syndrome is an X‐linked neurodevelopmental disorder caused by mutation of Mecp2
gene and primarily affects females. Glial cell dysfunction has been implicated in in Rett …

Background: Elevated glutamate production and release from glial cells is a common feature
of many CNS disorders. Inhibitors of glutaminase (GLS), the enzyme responsible for …

Activated microglia/macrophages have been implicated as key players in many central
nervous system (CNS) diseases, such as brain tumor and Rett syndrome, in which they …

Background Microglial cells have been implicated in neuroinflammation-mediated injury in
the brain, including neurodevelopmental disorders such as cerebral palsy (CP) and autism …

Neuroinflammation, mediated by activated microglia and astrocytes, plays a key role in the
pathogenesis of many neurological disorders. Systemically-administered dendrimers target …

Effective treatment of many CNS diseases remains a major challenge due to the lack of
specificity for therapeutics to target pathological cells. Many nanoparticles offer promising …

Background Neuroinflammation mediated by microglia plays a central role in the
pathogenesis of perinatal/neonatal brain injury, including cerebral palsy (CP). Therapeutics …