Abstract Background Glial contributions to Alzheimer's disease (AD) etiology and
progression have been increasingly recognized. Experimental and clinical evidence …

An unresolved question for the understanding of Alzheimer's disease (AD) pathophysiology
is why a significant percentage of amyloid β (Aβ)-positive cognitively unimpaired (CU) …

Background Activation of microglial cells in the brain, more commonly known as
neuroinflammation, has often been linked to the pathophysiology of Alzheimer's disease …

Background A significant percentage of Aβ‐positive cognitively unimpaired (CU) individuals
do not develop detectable downstream tau pathology and, consequently, cognitive decline …

Background Aβ accumulation precedes tau pathology in cognitively unimpaired (CU)
individuals, which is an event closely related to the development of cognitive symptoms …

Background Deposition of amyloid‐beta (Aβ) plaques and hyperphosphorylated tau are
known hallmarks of Alzheimer's disease (AD). In addition, neuroinflammation or microglia …

Astrocytes are fast climbing the ladder of importance in neurodegenerative disorders,
particularly in Alzheimer's Disease (AD), with the prominent presence of reactive astrocytes …

Alzheimer's disease (AD) affects various brain cell types, including astrocytes, which are the
most abundant cell types in the central nervous system (CNS). Astrocytes not only provide …

Background Neuroinflammation plays a significant role in the pathogenesis of AD. Here, we
evaluate neuroinflammation, the interrelationship between neuroinflammation, amyloid and …

Alzheimer's disease (AD) is a neurodegenerative disorder that usually develops slowly and
progressively worsens over time. Although there has been increasing research interest in …