The molecular diversity of receptors in human blood vessels remains largely unexplored.
We developed a selection method in which peptides that home to specific vascular beds are …

The vascular endothelium expresses differential receptors depending on the functional state
and tissue localization of its cells. A method to characterize this receptor heterogeneity with …

PREFERENTIAL homing of tumour cells1, 2 and leukocytes3, 4 to specific organs indicates
that tissues carry unique marker molecules accessible to circulating cells. Organ-selective …

We have isolated several organ-and tumor-homing peptides by using in vivo phage display.
This technology involves the screening of peptide libraries in a living animal. The peptides …

Selectivity of tissue expression for surface molecules of cells lining the vasculature has been
uncovered in disease and during normal development. Systematic profiling of selectively …

In vivo screening of phage-displayed peptide libraries has revealed extensive molecular
differences in the blood vessels of individual normal tissues. Pathological lesions also put …

In vivo selection of phage display libraries was used to isolate peptides that home
specifically to tumor blood vessels. When coupled to the anticancer drug doxorubicin, two of …

Peptides possess appropriate pharmacokinetic properties to serve as cancer imaging or
therapeutic targeting agents. Currently, only a small number of rationally‐derived, labeled …

Here we introduce a new approach for the screening, selection and sorting of cell-surface–
binding peptides from phage libraries. Biopanning and rapid analysis of selective interactive …

Blood vessels of tumors carry specific markers that are usually angiogenesis-related,. We
previously used phage-displayed peptide libraries in vivo to identify peptides that home to …