Universal hepatitis B vaccination in Taiwan and the incidence of hepatocellular carcinoma in children

MH Chang, CJ Chen, MS Lai, HM Hsu… - … England Journal of …, 1997 - Mass Medical Soc
Background A nationwide hepatitis B vaccination program was implemented in Taiwan in
July 1984. To assess the effect of the program on the development of hepatocellular …

Hepatitis B vaccination and hepatocellular carcinoma in Taiwan

CL Lee, YC Ko - Pediatrics, 1997 - publications.aap.org
Objective. In 1984, Taiwan started a large-scale hepatitis B vaccination program, enabling
us to test the hypothesis that prevention of hepatitis B virus infection eventually decreases …

Hepatitis B vaccination and hepatocellular carcinoma rates in boys and girls

MH Chang, WY Shau, CJ Chen, TC Wu, MS Kong… - Jama, 2000 - jamanetwork.com
ContextHepatocellular carcinoma (HCC) has a male predominance and is closely related to
hepatitis B virus (HBV) infection. Hepatitis B virus vaccination was launched in 1984 in …

Prevention of hepatocellular carcinoma by universal vaccination against hepatitis B virus: the effect and problems

MH Chang, THH Chen, HM Hsu, TC Wu, MS Kong… - Clinical cancer …, 2005 - AACR
Purpose: In spite of the success of hepatitis B immunization, still a significant proportion of
childhood hepatocellular carcinoma (HCC) failed to be prevented by the hepatitis B …

Hepatitis B vaccination in children: the Taiwan experience

YH Ni, DS Chen - Pathologie Biologie, 2010 - Elsevier
The world's first nationwide hepatitis B virus (HBV) universal vaccination program for infants
was launched in Taiwan in July, 1984. All infants received three to four doses plasma or …

Decreasing incidence of hepatocellular carcinoma among children following universal hepatitis B immunization

MH Chang - Liver international, 2003 - Wiley Online Library
Hepatocellular carcinoma (HCC) is one of the 10 most common malignant tumors
worldwide. Chronic infection with hepatitis B or C virus is closely related to …

Decreased incidence of hepatocellular carcinoma in hepatitis B vaccinees: a 20-year follow-up study

MH Chang, SL You, CJ Chen, CJ Liu… - Journal of the …, 2009 - academic.oup.com
Abstract Background Hepatitis B virus (HBV) infection is a major cause of hepatocellular
carcinoma. This population-based study aimed to investigate whether prevention of …

Nationwide hepatitis B vaccination program in Taiwan: effectiveness in the 20 years after it was launched

YC Chien, CF Jan, HS Kuo, CJ Chen - Epidemiologic reviews, 2006 - academic.oup.com
The national hepatitis B vaccination program in Taiwan is considered one of the most
successful and effective public health programs to control chronic hepatitis B infection in the …

Nationwide vaccination: a success story in Taiwan

KY Huang, SR Lin - Vaccine, 2000 - Elsevier
In the early 1980s, 15–20% of the population of Taiwan were estimated to be hepatitis B
virus (HBV) carriers. A programme of mass vaccination against hepatitis B was therefore …

Legend of hepatitis B vaccination: the Taiwan experience

CHOYU CHAN, SD LEE, KJ LO - Journal of gastroenterology …, 2004 - Wiley Online Library
Hepatitis B, a disease entity currently affecting more than 350 million persons worldwide, is
also a serious health problem in Taiwan. Liver cirrhosis and hepatoma, which are both …