Inflammatory bowel disease: clinical aspects and established and evolving therapies

DC Baumgart, WJ Sandborn - The Lancet, 2007 - thelancet.com
Crohn's disease and ulcerative colitis are two idiopathic inflammatory bowel disorders. In
this paper we discuss the current diagnostic approach, their pathology, natural course, and …

De-escalation of immunomodulator and biological therapy in inflammatory bowel disease

TP Chapman, CF Gomes, E Louis… - The Lancet …, 2020 - thelancet.com
Treatment strategies for inflammatory bowel disease (IBD) focus on the induction and long-
term maintenance of deep remission to avoid complications of active disease and improve …

Inflammatory bowel disease: cause and immunobiology

DC Baumgart, SR Carding - The Lancet, 2007 - thelancet.com
Crohn's disease and ulcerative colitis are idiopathic inflammatory bowel disorders. In this
paper, we discuss how environmental factors (eg, geography, cigarette smoking, sanitation …

[HTML][HTML] New strategies for treatment of inflammatory bowel disease

OH Nielsen - Frontiers in medicine, 2014 - frontiersin.org
The etiology of inflammatory bowel disease (IBD), of which ulcerative colitis (UC) and
Crohn's disease (CD) are the two most prevailing entities, is unknown. However, IBD is …

Biologic therapies in inflammatory bowel disease

LB Cohen, RM Nanau, F Delzor, MG Neuman - Translational Research, 2014 - Elsevier
Inflammatory bowel disease, including its 2 entities ulcerative colitis and Crohn's disease, is
a chronic medical condition characterized by the destructive inflammation of the intestinal …

Crohn's disease

F Shanahan - The Lancet, 2002 - thelancet.com
Crohn's disease is a disorder mediated by Tlymphocyteswhich arises in genetically
susceptible individuals as a result of a breakdown in the regulatory constraints on mucosal …

[HTML][HTML] Emerging therapies for inflammatory bowel disease

R Weisshof, K El Jurdi, N Zmeter, DT Rubin - Advances in therapy, 2018 - Springer
Inflammatory bowel disease (IBD) is a chronic heterogeneous group of diseases that has
undergone major advances in the understanding of its etiology and pathogenesis in recent …

[HTML][HTML] The diagnosis and treatment of Crohn's disease and ulcerative colitis

DC Baumgart - Deutsches Ärzteblatt International, 2009 - ncbi.nlm.nih.gov
Methods This is not a systematic review nor a meta-analysis. It is mainly based on the
guidelines of national (DGVS and DACED) and international (AGA, ACG, BSG, CCFA …

emerging drug therapies in inflammatory bowel disease

LB Grossberg, K Papamichael… - Alimentary …, 2022 - Wiley Online Library
Background The landscape of inflammatory bowel disease (IBD) treatment is rapidly
expanding with the development of new therapeutic options. Aim To review the mechanisms …

Novel therapies and treatment strategies for patients with inflammatory bowel disease

M Duijvestein, R Battat, N Vande Casteele… - … treatment options in …, 2018 - Springer
Purpose of review This article reviews current treatment options and strategies and provides
an update on the status of drug development programs of new therapeutic agents for …