Atherosclerosis and its complications such as stroke, myocardial infraction and peripheral
vascular disease, remain the major causes of morbidity and mortality in the world. Studies …

Background The induction of vascular cell adhesion molecule–1 (VCAM-1) and E-selectin
by tumor necrosis factor–α (TNF) is mediated by mobilization of the transcription factor …

In the development of atherosclerosis, inflammatory cells adhere to and migrate into the
vascular walls by interacting with vascular smooth muscle cells. To investigate the …

Activated endothelial cells express monocyte chemoattractant protein-1 (MCP-1), a
chemokine which is reportedly involved in the recruitment of plasma monocytes in the early …

Background Inflammatory related cardiovascular disease, ie cardiac allograft rejection,
myocarditis, septic shock, are accompanied by cytokine production, which stimulates the …

In a previous study, it was reported that stimulation with a TXA2 receptor agonist, U46619,
augments the expression of adhesion molecules by human umbilical vein endothelial cells …

Recently, aspirin has been shown to alleviate matrix metalloproteinase (MMP) expression,
but the underlying mechanism is still unclear. In this study, the effects of aspirin on oxidative …

Aspirin has antithrombotic activity and is commonly used to protect patients from
cardiovascular disease attacks. The present study investigated whether aspirin reduces …

Leukocyte adhesion and transmigration through the endothelial cell (EC) layer plays a
crucial role in inflammation. IL-lα and TNFα increase EC-adhesiveness for leukocytes by …

Abstract Interleukin 1 (IL-1), bacterial lipopolysaccharide (LPS) and tumor necrosis factor
(TNFα) enhance the adherence properties of endothelial cells (EC) for neutrophils (PMN) …