In this investigation, 18 children developed AKI based on adjusted SCr definition, with a
frequency of AKI of 25.9% in the PTZ+ vancomycin group and 8.6% in the ceftriaxone+ …

Objectives: Compare the rates of acute kidney injury in critically ill children treated with
vancomycin and piperacillin-tazobactam versus vancomycin and ceftriaxone. Design …

Background There continues to be uncertainty about whether piperacillin/tazobactam (TZP)
increases the risk of AKI in critically ill pediatric patients. We sought to compare rates of AKI …

Importance β-Lactam antibiotics are often coadministered with intravenous (IV) vancomycin
hydrochloride for children with suspected serious infections. For adults, the combination of …

Background Previous literature showed a higher incidence of acute kidney injury (AKI) in
pediatric patients using vancomycin+ piperacillin-tazobactam compared to cefepime+ …

When considering the risk of acute kidney injury (AKI), no antibiotic regimen has received
more attention recently than the vancomycin (VN) plus piperacillin–tazobactam (PT) …

Background: Several studies have shown that vancomycin combined with piperacillin/
tazobactam (VPT) increased the risk of acute kidney injury (AKI) compared with other …

Background. Vancomycin and piperacillin‐tazobactam (PTZ) are commonly used as
empirical therapy for patients with health care associated infections. Vancomycin has been …

OBJECTIVES To determine whether combination therapy with vancomycin and TZP is
associated with a higher incidence of acute kidney injury (AKI) compared with vancomycin …

Purpose Results of a study of rates of acute kidney injury (AKI) in pediatric patients treated
with vancomycin plus piperacillin–tazobactam or vancomycin plus alternative …