Design and validation of a supragenome array for determination of the genomic content of Haemophilus influenzae isolates

RA Eutsey, NL Hiller, JP Earl, BA Janto, ME Dahlgren… - BMC genomics, 2013 - Springer
Background Haemophilus influenzae colonizes the human nasopharynx as a commensal,
and is etiologically associated with numerous opportunistic infections of the airway; it is also …

Investigations into genome diversity of Haemophilus influenzae using whole genome sequencing of clinical isolates and laboratory transformants

PM Power, SD Bentley, J Parkhill, ER Moxon… - BMC microbiology, 2012 - Springer
Background Haemophilus influenzae is an important human commensal pathogen
associated with significant levels of disease. High-throughput DNA sequencing was used to …

Development and Validation of an Haemophilus influenzae Supragenome Hybridization (SGH) Array for Transcriptomic Analyses

BA Janto, NL Hiller, RA Eutsey, ME Dahlgren, JP Earl… - PLoS …, 2014 - journals.plos.org
We previously carried out the design and testing of a custom-built Haemophilus influenzae
supragenome hybridization (SGH) array that contains probe sequences to 2,890 gene …

Haemophilus influenzae: using comparative genomics to accurately identify a highly recombinogenic human pathogen

EP Price, DS Sarovich, E Nosworthy, J Beissbarth… - BMC genomics, 2015 - Springer
Background Haemophilus influenzae is an opportunistic bacterial pathogen that exclusively
colonises humans and is associated with both acute and chronic disease. Despite its clinical …

Characterization and modeling of the Haemophilus influenzae core and supragenomes based on the complete genomic sequences of Rd and 12 clinical …

JS Hogg, FZ Hu, B Janto, R Boissy, J Hayes, R Keefe… - Genome biology, 2007 - Springer
Background The distributed genome hypothesis (DGH) posits that chronic bacterial
pathogens utilize polyclonal infection and reassortment of genic characters to ensure …

Haemophilus influenzae Genome Database (HIGDB): a single point web resource for Haemophilus influenzae

RG Swetha, DKK Sekar, S Ramaiah… - Computers in biology …, 2014 - Elsevier
Abstract Background Haemophilus influenzae (H. Influenzae) is the causative agent of
pneumonia, bacteraemia and meningitis. The organism is responsible for large number of …

Insights into the population structure and pan-genome of Haemophilus influenzae

M Pinto, A González-Díaz, MP Machado… - Infection, Genetics and …, 2019 - Elsevier
The human-restricted bacterium Haemophilus influenzae is responsible for respiratory
infections in both children and adults. While colonization begins in the upper airways, it can …

[HTML][HTML] Genome-Scale Approaches to Identify Genes Essential for Haemophilus influenzae Pathogenesis

SMS Wong, BJ Akerley - Frontiers in cellular and infection …, 2012 - frontiersin.org
Haemophilus influenzae is a Gram-negative bacterium that has no identified natural niche
outside of the human host. It primarily colonizes the nasopharyngeal mucosa in an …

Draft genome sequences of three nontypeable strains of Haemophilus influenzae, C188, R535, and 1200, isolated from different types of disease

U Kappler, R Dhouib, RP Nair… - Genome …, 2017 - Am Soc Microbiol
Nontypeable Haemophilus influenzae is a persistent human respiratory pathogen known to
be involved in a range of acute and chronic respiratory diseases. Here, we report the …

Nontypeable Haemophilus influenzae Genetic Islands Associated with Chronic Pulmonary Infection

L Zhang, J Xie, M Patel, A Bakhtyar, GD Ehrlich… - 2012 - journals.plos.org
Background Haemophilus influenzae (Hi) colonizes the human respiratory tract and is an
important pathogen associated with chronic obstructive pulmonary disease (COPD) …