The IRT1 protein from Arabidopsis thaliana is a metal transporter with a broad substrate range

YO Korshunova, D Eide, W Gregg Clark… - Plant molecular …, 1999 - Springer
The molecular basis for the transport of manganese across membranes in plant cells is
poorly understood. We have found that IRT1, an Arabidopsis thaliana metal ion transporter …

Expression of the IRT1 metal transporter is controlled by metals at the levels of transcript and protein accumulation

EL Connolly, JP Fett, ML Guerinot - The Plant Cell, 2002 - academic.oup.com
Iron, an essential nutrient, is not readily available to plants because of its low solubility. In
addition, iron is toxic in excess, catalyzing the formation of hydroxyl radicals that can …

Knock-out of Arabidopsis metal transporter gene IRT1 results in iron deficiency accompanied by cell differentiation defects

R Henriques, J Jásik, M Klein, E Martinoia… - Plant molecular …, 2002 - Springer
IRT1 and IRT2 are members of the Arabidopsis ZIP metal transporter family that are
specifically induced by iron deprivation in roots and act as heterologous suppressors of …

Arabidopsis IRT2 gene encodes a root‐periphery iron transporter

G Vert, JF Briat, C Curie - The Plant Journal, 2001 - Wiley Online Library
Iron uptake from the soil is a tightly controlled process in plant roots, involving specialized
transporters. One such transporter, IRT1, was identified in Arabidopsis thaliana and shown …

Altered selectivity in an Arabidopsis metal transporter

EE Rogers, DJ Eide… - Proceedings of the …, 2000 - National Acad Sciences
Plants require metals for essential functions ranging from respiration to photosynthesis.
These metals also contribute to the nutritional value of plants for both humans and livestock …

IRT1, an Arabidopsis transporter essential for iron uptake from the soil and for plant growth

G Vert, N Grotz, F Dédaldéchamp, F Gaymard… - The plant …, 2002 - academic.oup.com
Plants are the principal source of iron in most diets, yet iron availability often limits plant
growth. In response to iron deficiency, Arabidopsis roots induce the expression of the …

The metal ion transporter IRT1 is necessary for iron homeostasis and efficient photosynthesis in Arabidopsis thaliana

C Varotto, D Maiwald, P Pesaresi, P Jahns… - The Plant …, 2002 - Wiley Online Library
The mutants irt1‐1 and irt1‐2 of Arabidopsis thaliana were identified among a collection of T‐
DNA‐tagged lines on the basis of a decrease in the effective quantum yield of photosystem …

A novel iron-regulated metal transporter from plants identified by functional expression in yeast.

D Eide, M Broderius, J Fett… - Proceedings of the …, 1996 - National Acad Sciences
Iron is an essential nutrient for virtually all organisms. The IRT1 (iron-regulated transporter)
gene of the plant Arabidopsis thaliana, encoding a probable Fe (II) transporter, was cloned …

Iron-induced turnover of the Arabidopsis IRON-REGULATED TRANSPORTER1 metal transporter requires lysine residues

L Kerkeb, I Mukherjee, I Chatterjee, B Lahner… - Plant …, 2008 - academic.oup.com
Iron is an essential micronutrient but is toxic if accumulated at high levels. Thus, iron uptake
and distribution in plants are controlled by precise regulatory mechanisms. IRON …

Arabidopsis IRT3 is a zinc‐regulated and plasma membrane localized zinc/iron transporter

YF Lin, HM Liang, SY Yang, A Boch… - New …, 2009 - Wiley Online Library
ZIP transporters (ZRT, IRT‐like proteins) are involved in the transport of iron (Fe), zinc (Zn)
and other divalent metal cations. The expression of IRT3, a ZIP transporter, is higher in the …