Serine 477 plays a crucial role in the interaction of the SARS-CoV-2 spike protein with the human receptor ACE2
Since the worldwide outbreak of the infectious disease COVID-19, several studies have
been published to understand the structural mechanism of the novel coronavirus SARS-CoV …
been published to understand the structural mechanism of the novel coronavirus SARS-CoV …
SARS-CoV-2 spike protein: flexibility as a new target for fighting infection
CL Pierri - Signal Transduction and Targeted Therapy, 2020 - nature.com
The spike protein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
crucial for the infection because it mediates the virus entry into human host-cells, through …
crucial for the infection because it mediates the virus entry into human host-cells, through …
Interactions of angiotensin-converting enzyme-2 (ACE2) and SARS-CoV-2 spike receptor-binding domain (RBD): a structural perspective
Abstract Background Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has
caused millions of infections and deaths worldwide since its discovery in late 2019 in …
caused millions of infections and deaths worldwide since its discovery in late 2019 in …
Key residues of the receptor binding motif in the spike protein of SARS-CoV-2 that interact with ACE2 and neutralizing antibodies
C Yi, X Sun, J Ye, L Ding, M Liu, Z Yang, X Lu… - Cellular & molecular …, 2020 - nature.com
Abstract Coronavirus disease 2019 (COVID-19), caused by the novel human coronavirus
SARS-CoV-2, is currently a major threat to public health worldwide. The viral spike protein …
SARS-CoV-2, is currently a major threat to public health worldwide. The viral spike protein …
Interaction of the spike protein RBD from SARS-CoV-2 with ACE2: Similarity with SARS-CoV, hot-spot analysis and effect of the receptor polymorphism
H Othman, Z Bouslama, JT Brandenburg… - Biochemical and …, 2020 - Elsevier
The spread of COVID-19 caused by the SARS-CoV-2 outbreak has been growing since its
first identification in December 2019. The publishing of the first SARS-CoV-2 genome made …
first identification in December 2019. The publishing of the first SARS-CoV-2 genome made …
Molecular mechanism of the N501Y mutation for enhanced binding between SARS-CoV-2's spike protein and human ACE2 receptor
Abstract Coronavirus disease 2019 (COVID-19) has been an ongoing global pandemic for
over a year. Recently, an emergent SARS-CoV-2 variant (B. 1.1. 7) with an unusually large …
over a year. Recently, an emergent SARS-CoV-2 variant (B. 1.1. 7) with an unusually large …
Protein structure analysis of the interactions between SARS-CoV-2 spike protein and the human ACE2 receptor: from conformational changes to novel neutralizing …
I Mercurio, V Tragni, F Busto, A De Grassi… - Cellular and Molecular …, 2021 - Springer
The recent severe acute respiratory syndrome, known as Coronavirus Disease 2019
(COVID-19) has spread so much rapidly and severely to induce World Health Organization …
(COVID-19) has spread so much rapidly and severely to induce World Health Organization …
Mutation N501Y in RBD of Spike Protein Strengthens the Interaction between COVID-19 and its Receptor ACE2
ABSTRACT SARS-CoV-2 is spreading around the world for the past year. Enormous efforts
have been taken to understand its mechanism of transmission. It is well established now that …
have been taken to understand its mechanism of transmission. It is well established now that …
The SARS-CoV-2 spike glycoprotein as a drug and vaccine target: structural insights into its complexes with ACE2 and antibodies
AC Papageorgiou, I Mohsin - Cells, 2020 - mdpi.com
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the causative agent of
the Coronavirus disease (COVID-19) pandemic, has so far resulted in more than 1.1 M …
the Coronavirus disease (COVID-19) pandemic, has so far resulted in more than 1.1 M …
Evolutionary and structural analysis elucidates mutations on SARS-CoV2 spike protein with altered human ACE2 binding affinity
S Chakraborty - Biochemical and biophysical research communications, 2021 - Elsevier
The recognition of ACE2 by the receptor-binding domain (RBD) of spike protein mediates
host cell entry. The objective of the work is to identify SARS-CoV2 spike variants that …
host cell entry. The objective of the work is to identify SARS-CoV2 spike variants that …
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