Anti-kindling effect of Ginkgo biloba leaf extract and L-carnitine in the pentylenetetrazol model of epilepsy

AE Essawy, SA El-Sayed, E Tousson… - … Science and Pollution …, 2022 - Springer
Epilepsy is one of the most common serious brain disorders, affecting about 1% of the
population all over the world. Ginkgo biloba extract (GbE) and L-carnitine (LC) reportedly …

Protective effect of naringin on pentylenetetrazole (PTZ)-induced kindling; possible mechanisms of antikindling, memory improvement, and neuroprotection

PK Kola, A Akula, LS NissankaraRao… - Epilepsy & Behavior, 2017 - Elsevier
The present study investigated the effects of Naringin on seizure severity, progress of
kindling, memory impairment, oxidative stress, neurochemicals, and neural damage in …

Neuroprotective effect of lycopene against PTZ‐induced kindling seizures in mice: Possible behavioural, biochemical and mitochondrial dysfunction

M Bhardwaj, A Kumar - Phytotherapy Research, 2016 - Wiley Online Library
Oxidative stress and mitochondrial dysfunction are the major contributing factors in the
pathophysiology of various neurological disorders. Recently, antioxidant therapies aimed at …

Antiepileptogenic effect of curcumin on kainate-induced model of temporal lobe epilepsy

Z Kiasalari, M Roghani, M Khalili, B Rahmati… - Pharmaceutical …, 2013 - Taylor & Francis
Context: Temporal lobe epilepsy (TLE) is an intractable neurological disorder. Curcumin is
the bioactive component of turmeric with anti-epileptic and neuroprotective potential …

Effects of epigallocatechin-3-gallate on pentylenetetrazole-induced kindling, cognitive impairment and oxidative stress in rats

T Xie, W Wang, Z Mao, Z Qu, S Luan, L Jia, M Kan - Neuroscience Letters, 2012 - Elsevier
Cognitive dysfunction is commonly observed in epileptic patients. It has been shown that not
only epilepsy but also antiepileptic drugs could induce cognitive impairment. Thus, there is …

Pentylenetetrazol-induced kindling seizure attenuated by Ginkgo biloba extract (EGb 761) in mice

A Ilhan, M Iraz, S Kamisli, R Yigitoglu - Progress in Neuro …, 2006 - Elsevier
Ginkgo biloba extract (EGb 761) has been used therapeutically for centuries. It has attracted
great attention as agents for improving circulation, particularly cerebral circulation, which …

The Neuroprotective Effect of Curcumin and Nigella sativa Oil Against Oxidative Stress in the Pilocarpine Model of Epilepsy: A Comparison with Valproate

HS Aboul Ezz, YA Khadrawy, NA Noor - Neurochemical research, 2011 - Springer
Oxidative stress has been implicated to play a role in epileptogenesis and pilocarpine-
induced seizures. The present study aims to evaluate the antioxidant effects of curcumin …

Effect of Centella asiatica on pentylenetetrazole-induced kindling, cognition and oxidative stress in rats

YK Gupta, MHV Kumar, AK Srivastava - Pharmacology Biochemistry and …, 2003 - Elsevier
Cognitive impairment in epileptics may be a consequence of the epileptogenic process as
well as antiepileptic medication. Thus, there is a need for drugs, which can suppress …

Acteoside Isolated from Colebrookea oppositifolia Smith Attenuates Epilepsy in Mice Via Modulation of Gamma-Aminobutyric Acid Pathways

GL Viswanatha, H Shylaja, DV Kishore… - Neurotoxicity …, 2020 - Springer
The present study was aimed to evaluate the anticonvulsant activity of acteoside and
explore its mechanism of action. Initially, the acteoside was evaluated in maximal …

[HTML][HTML] Anti-oxidant and anti-apoptotic effects of berberine in pentylenetetrazole-induced kindling model in rat

V Guna, L Saha, A Bhatia, D Banerjee… - Journal of Epilepsy …, 2018 - ncbi.nlm.nih.gov
Background and Purpose Berberine (BBR) is derived from the Berberis species and has
demonstrated beneficial effects in various neurodegenerative disorders in animal models …