Immune mechanisms of hypertension

GR Drummond, A Vinh, TJ Guzik… - Nature Reviews …, 2019 - nature.com
Hypertension affects 30% of adults and is the leading risk factor for heart attack and stroke.
Traditionally, hypertension has been regarded as a disorder of two systems that are involved …

Role of immune cells in hypertension

A Caillon, P Paradis, EL Schiffrin - British journal of …, 2019 - Wiley Online Library
Inflammatory processes have been shown to play an important role in the mechanisms
involved in the pathogenesis of hypertension. Innate and adaptive immune responses …

Immunity and hypertension

RM Zhang, KP McNerney, AE Riek… - Acta …, 2021 - Wiley Online Library
Hypertension is the primary cause of cardiovascular mortality. Despite multiple existing
treatments, only half of those with the disease achieve adequate control. Therefore …

Role of the adaptive immune system in hypertension

DG Harrison, A Vinh, H Lob, MS Madhur - Current opinion in pharmacology, 2010 - Elsevier
Recent studies have shown that both innate and adaptive immunity contribute to
hypertension. Inflammatory cells, including macrophages and T cells accumulate in the …

Immune mechanisms in hypertension

A Leibowitz, EL Schiffrin - Current hypertension reports, 2011 - Springer
Inflammation plays an important role in the pathogenesis of hypertension. Innate and
adaptive immune response may contribute to this process. The mechanisms implicating …

Role of the immune system in hypertension

B Rodriguez-Iturbe, H Pons… - Physiological …, 2017 - journals.physiology.org
High blood pressure is present in more than one billion adults worldwide and is the most
important modifiable risk factor of death resulting from cardiovascular disease. While many …

Innate immunity and clinical hypertension

JP Van Beusecum, H Moreno… - Journal of human …, 2022 - nature.com
Emerging evidence has supported a role of inflammation and immunity in the genesis of
hypertension. In humans and experimental models of hypertension, cells of the innate and …

[HTML][HTML] Novel immune mechanisms in hypertension and cardiovascular risk

R Nosalski, E McGinnigle, M Siedlinski… - … cardiovascular risk reports, 2017 - Springer
Abstract Purpose of Review Hypertension is a common disorder with substantial impact on
public health due to highly elevated cardiovascular risk. The mechanisms still remain …

Inflammation, immunity, and hypertension

DG Harrison, TJ Guzik, HE Lob, MS Madhur… - …, 2011 - Am Heart Assoc
Aprominent pathology textbook used in the United States includes an image illustrating the
renal histopathology caused by malignant hypertension. The legend describes striking …

Therapeutic targeting of inflammation in hypertension: from novel mechanisms to translational perspective

EC Murray, R Nosalski, N MacRitchie… - Cardiovascular …, 2021 - academic.oup.com
Both animal models and human observational and genetic studies have shown that immune
and inflammatory mechanisms play a key role in hypertension and its complications. We …