[HTML][HTML] Quantification of ricin, RCA and comparison of enzymatic activity in 18 Ricinus communis cultivars by isotope dilution mass spectrometry

DM Schieltz, LG McWilliams, Z Kuklenyik, SM Prezioso… - Toxicon, 2015 - Elsevier
The seeds of the Ricinus communis (Castor bean) plant are the source of the economically
important commodity castor oil. Castor seeds also contain the proteins ricin and R …

[HTML][HTML] Recommended mass spectrometry-based strategies to identify ricin-containing samples

SR Kalb, DM Schieltz, F Becher, C Astot… - Toxins, 2015 - mdpi.com
Ricin is a protein toxin produced by the castor bean plant (Ricinus communis) together with
a related protein known as R. communis agglutinin (RCA120). Mass spectrometric (MS) …

Selection of Castor for Divergent Concentrations of Ricin and Ricinus communis Agglutinin

SD Pinkerton, R Rolfe, DL Auld, V Ghetie… - Crop …, 1999 - Wiley Online Library
One of the most limiting factors in the production and processing of castor (Ricinus
communis L.) is the presence of ricin and Ricinus communis agglutinin (RCA) in the …

Ricin accumulation and degradation during castor seed development and late germination

DJ Barnes, BS Baldwin, DA Braasch - Industrial Crops and Products, 2009 - Elsevier
The castor plant (Ricinus communis L.) is a euphorb, commonly grown for its high seed oil
content. The seed also contains a deadly toxin known as ricin (RCA60) and the less toxic …

Liquid Chromatography–Mass Spectrometry and Chemometric Analysis of Ricinus communis Extracts for Cultivar Identification

SPB Ovenden, EJ Pigott, S Rochfort… - Phytochemical …, 2014 - Wiley Online Library
ABSTRACT Introduction Seeds of Ricinus communis contain the toxic protein ricin, a 64 kD
heterodimeric type II ribosome‐inactivating protein that has been used in several high …

Purification, characterization and toxicity profile of ricin isoforms from castor beans

P Sehgal, M Khan, O Kumar… - Food and Chemical …, 2010 - Elsevier
The castor seed contains the toxin ricin, one of the most poisonous naturally occurring
toxins. The whole of the plant is poisonous, however the seeds are considered the major …

Development of monoclonal antibodies specific for Ricinus agglutinins

DL Brandon, BJ Hernlem - Food and agricultural immunology, 2009 - Taylor & Francis
Ricin is a highly toxic, dichain ribosome-inactivating protein present in the seeds of Ricinus
communis (castor), grown principally as a source of high quality industrial lubricant and as …

Characterization of ricin heterogeneity by electrospray mass spectrometry, capillary electrophoresis, and resonant mirror

D Despeyroux, N Walker, M Pearce, M Fisher… - Analytical …, 2000 - Elsevier
Electrospray mass spectrometry (ES/MS), capillary-zone electrophoresis (CZE), capillary
isoelectric focusing (CIEF), and multianalyte resonant mirror are used to evaluate the …

Broad recognition of ricin toxins prepared from a range of Ricinus cultivars using immunochromatographic tests

P Thullier, G Griffiths - Clinical Toxicology, 2009 - Taylor & Francis
Introduction. It is extremely important that diagnosis of persons exposed to ricin be achieved
in a timely fashion for triage and appropriate treatment. A sensitive and specific …

Rapid and sensitive identification of ricin in environmental samples based on lactamyl agarose beads using LC‐MS/MS (MRM)

L Feldberg, O Schuster, E Elhanany… - Journal of Mass …, 2020 - Wiley Online Library
Ricin, a plant‐derived toxin extracted from the seeds of Ricinus communis (castor bean
plant), is one of the most toxic proteins known. Ricin's high toxicity, widespread availability …