Nanoemulsion as a potential ophthalmic delivery system for dorzolamide hydrochloride

HO Ammar, HA Salama, M Ghorab, AA Mahmoud - Aaps Pharmscitech, 2009 - Springer
Dilutable nanoemulsions are potent drug delivery vehicles for ophthalmic use due to their
numerous advantages as sustained effect and high ability of drug penetration into the …

Therapeutic nanoemulsions in ophthalmic drug administration: Concept in formulations and characterization techniques for ocular drug delivery

M Singh, S Bharadwaj, KE Lee, SG Kang - Journal of Controlled Release, 2020 - Elsevier
The eye is the specialized part of the body and is comprised of numerous physiological
ocular barriers that limit the drug absorption at the action site. Regardless of various efforts …

Development of dorzolamide hydrochloride in situ gel nanoemulsion for ocular delivery

HO Ammar, HA Salama, M Ghorab… - Drug development and …, 2010 - Taylor & Francis
Background: Several in situ gel-forming systems have been developed to prolong the
precorneal residence time of a drug and to improve ocular bioavailability. Poloxamer 407 …

[HTML][HTML] Nanoemulsions as ophthalmic drug delivery systems

RK Dhahir, AM Al-Nima, ALB Fadia - Turkish Journal of …, 2021 - ncbi.nlm.nih.gov
Nanoemulsions are liquid-in-liquid dispersion with a droplet size of about 100 nm. They
have a transparent appearance, high rate of bioavailability, and increased shelf life …

A comprehensive review on nanoemulsion as an ophthalmic drug delivery system

BR Choradiya, SB Patil - Journal of Molecular Liquids, 2021 - Elsevier
Nanoemulsions formulated for the ocular drug delivery have a good scope in
pharmaceutical products due to the transparency at enlarged droplet volume fraction …

Topical drug delivery to the eye: dorzolamide

T Loftsson, P Jansook, E Stefansson - Acta Ophthalmologica, 2012 - Wiley Online Library
Topically applied carbonic anhydrase inhibitors (CAIs) in eye drop solutions are commonly
used to treat glaucoma. However, local eye irritation and multiple daily administrations may …

Nanoemulsion based vehicle for effective ocular delivery of moxifloxacin using experimental design and pharmacokinetic study in rabbits

J Shah, AB Nair, S Jacob, RK Patel, H Shah… - Pharmaceutics, 2019 - mdpi.com
Nanoemulsion is one of the potential drug delivery strategies used in topical ocular therapy.
The purpose of this study was to design and optimize a nanoemulsion-based system to …

Successfully improving ocular drug delivery using the cationic nanoemulsion, novasorb

F Lallemand, P Daull, S Benita… - Journal of drug …, 2012 - Wiley Online Library
Topical ophthalmic delivery of active ingredients can be achieved using cationic
nanoemulsions. In the last decade, Novagali Pharma has successfully developed and …

Development of O/W nanoemulsions for ophthalmic administration of timolol

M Gallarate, D Chirio, R Bussano, E Peira… - International journal of …, 2013 - Elsevier
After an initial screening of ingredients and production methods, nanoemulsions for ocular
administration of timolol containing the drug as maleate (TM) or as ion-pair with AOT …

Nanotechnology in ocular drug delivery

SK Sahoo, F Dilnawaz, S Krishnakumar - Drug discovery today, 2008 - Elsevier
Despite numerous scientific efforts, efficient ocular drug delivery remains a challenge for
pharmaceutical scientists. Most ocular diseases are treated by topical drug application in the …