Acute myeloid leukemia (AML) is a heterogeneous group of hematologic malignancies
characterized by the proliferation of myeloid cells blocked in their ability to differentiate …

Risk-stratification of acute myeloid leukemia (AML) based on recurrent somatic
abnormalities has evolved substantially in recent years, as illustrated by the current 2017 …

Acute myeloid leukemia (AML) is a clonal disorder resulting from acquired somatic
mutations in hematopoietic progenitor cells that lead to the dysregulation of differentiation …

Acute myeloid leukemia (AML) is characterized by recurrent genetic alterations, including
amplifications, deletions, rearrangements, and point mutations. Clinically, these lesions can …

Acute myeloid leukemia (AML) is a heterogeneous disorder characterized by a wide range
of genetic defects. Cytogenetics, molecular and genomic technologies have proved to be …

In recent years, our understanding of the molecular pathogenesis of myeloid neoplasms,
including acute myeloid leukemia (AML), has been greatly advanced by genomics discovery …

Background/Aim: Acute myeloid leukemia (AML) represents a heterogeneous disease with
varying morphologic, immunophenotypic, and genetic features, along with varying patient …

Since its use in the initial characterization of an acute myeloid leukemia (AML) genome, next‐
generation sequencing (NGS) has continued to molecularly refine the disease. Here, the …

Objectives To identify and characterize constitutional chromosomal rearrangements that
mimic recurrent genetic abnormalities in acute myeloid leukemia (AML). Methods Bone …

In recent years, the composite molecular architecture in acute myeloid leukemia (AML) has
been mapped out. We now have a clearer understanding of the key genetic determinants …