Verification and validation of bioinformatics software without a gold standard: a case study of BWA and Bowtie
Background Bioinformatics software quality assurance is essential in genomic medicine.
Systematic verification and validation of bioinformatics software is difficult because it is often …
Systematic verification and validation of bioinformatics software is difficult because it is often …
How to test bioinformatics software?
Bioinformatics is the application of computational, mathematical and statistical techniques to
solve problems in biology and medicine. Bioinformatics programs developed for …
solve problems in biology and medicine. Bioinformatics programs developed for …
An innovative approach for testing bioinformatics programs using metamorphic testing
Background Recent advances in experimental and computational technologies have fueled
the development of many sophisticated bioinformatics programs. The correctness of such …
the development of many sophisticated bioinformatics programs. The correctness of such …
[HTML][HTML] Scalability and validation of big data bioinformatics software
This review examines two important aspects that are central to modern big data
bioinformatics analysis–software scalability and validity. We argue that not only are the …
bioinformatics analysis–software scalability and validity. We argue that not only are the …
Evaluating genomic tests from bench to bedside: a practical framework
JS Lin, M Thompson, KAB Goddard, MA Piper… - BMC medical informatics …, 2012 - Springer
The development of genomic tests is one of the most significant technological advances in
medical testing in recent decades. As these tests become increasingly available, so does …
medical testing in recent decades. As these tests become increasingly available, so does …
Quality assurance of bioinformatics software: a case study of testing a biomedical text processing tool using metamorphic testing
M Srinivasan, MP Shahri, I Kahanda… - Proceedings of the 3rd …, 2018 - dl.acm.org
Bioinformatics software plays a very important role in making critical decisions within many
areas including medicine and health care. However, most of the research is directed …
areas including medicine and health care. However, most of the research is directed …
On best practices in the development of bioinformatics software
FV Leprevost, VC Barbosa, EL Francisco… - Frontiers in …, 2014 - frontiersin.org
Bioinformatics is one of the major areas of study in modern biology. Mediumand large-scale
quantitative biology studies have created a demand for professionals with proficiency in …
quantitative biology studies have created a demand for professionals with proficiency in …
[HTML][HTML] General guidelines for biomedical software development
Most bioinformatics tools available today were not written by professional software
developers, but by people that wanted to solve their own problems, using computational …
developers, but by people that wanted to solve their own problems, using computational …
Translational bioinformatics applications in genome medicine
AJ Butte - Genome Medicine, 2009 - Springer
Although investigators using methodologies in bioinformatics have always been useful in
genomic experimentation in analytic, engineering, and infrastructure support roles, only …
genomic experimentation in analytic, engineering, and infrastructure support roles, only …
A quick guide to genomics and bioinformatics training for clinical and public audiences
MD Brazas, F Lewitter, MV Schneider… - PLoS computational …, 2014 - journals.plos.org
Traditionally, bioinformatics tools and training programs have focused on life science
audiences. Though heterogeneous, their needs are at least fairly well understood. Driven by …
audiences. Though heterogeneous, their needs are at least fairly well understood. Driven by …