Chloride (Cl−) is the major extracellular anion in the body, accompanying sodium (Na+), and
is primarily derived from dietary sources. Data suggest that increased dietary Cl− intake …

Background Serum chloride level is routinely assayed in clinical laboratories in the
management of patients with kidney disorders and with metabolic diseases. It is a biological …

Background Electrolyte abnormalities, particularly dysnatremia, are independent predictors
of adverse outcome in individuals with and without renal failure. However, the association of …

Among the environmental factors that affect blood pressure, dietary sodium chloride has
been studied the most, and there is general consensus that increased sodium chloride …

Background We aimed to assess the association between alterations in serum chloride
levels during hospitalisation and mortality. Methods We reviewed all adult patients admitted …

Background Limited data suggest serum chloride levels associate with mortality in heart
failure, chronic kidney disease (CKD), and pulmonary arterial hypertension. Randomized …

Objective Research into dietary factors associated with hypertension has focused on the
sodium component of salt. However, chloride has distinct physiological effects that may …

Serum Cl (sCl) alterations in hospitalized patients have not been comprehensively studied
in recent years. The aim of this study is to investigate the prevalence and outcome …

Introduction This population-based study aimed to investigate the prognostic value of
ambulatory serum chloride abnormalities, often ignored by physicians. Methods The study …

Background Chloride administration has been found to be harmful to the kidney in critically
ill patients. However the association between plasma chloride concentration and renal …