Nanoenzyme-reinforced injectable hydrogel for healing diabetic wounds infected with multidrug resistant bacteria
Diabetic wound healing remains a critical challenge due to its vulnerability to multidrug-
resistant (MDR) bacterial infection, as well as the hyperglycemic and oxidative wound …
resistant (MDR) bacterial infection, as well as the hyperglycemic and oxidative wound …
Biomimetic Nanozyme-Decorated Hydrogels with H2O2-Activated Oxygenation for Modulating Immune Microenvironment in Diabetic Wound
Y Zhao, D Wang, T Qian, J Zhang, Z Li, Q Gong… - ACS …, 2023 - ACS Publications
Diabetic foot ulcers (DFUs) remain a devastating threat to human health. While hydrogels
are promising systems for DFU-based wound management, their effectiveness is often …
are promising systems for DFU-based wound management, their effectiveness is often …
Bio-fabricated nanocomposite hydrogel with ROS scavenging and local oxygenation accelerates diabetic wound healing
Chronic wounds, especially diabetic wounds, involve abnormally long inflammatory periods
due to their pathological microenvironment of high reactive oxygen species (ROS) levels …
due to their pathological microenvironment of high reactive oxygen species (ROS) levels …
Engineering bacteria‐activated multifunctionalized hydrogel for promoting diabetic wound healing
Y Lu, H Li, J Wang, M Yao, Y Peng, T Liu… - Advanced Functional …, 2021 - Wiley Online Library
Engineering therapeutic angiogenesis in impaired tissues is critical for chronic wound
healing. Materials can be engineered to deliver specific biological cues that enhance …
healing. Materials can be engineered to deliver specific biological cues that enhance …
Diabetes immunity-modulated multifunctional hydrogel with cascade enzyme catalytic activity for bacterial wound treatment
M Deng, M Zhang, R Huang, H Li, W Lv, X Lin… - Biomaterials, 2022 - Elsevier
Diabetes immunity-modulated wound treatment in response to the varied
microenvironments at different stages remains an urgent challenge. Herein, glucose oxidase …
microenvironments at different stages remains an urgent challenge. Herein, glucose oxidase …
All‐in‐one: multifunctional hydrogel accelerates oxidative diabetic wound healing through timed‐release of exosome and fibroblast growth factor
Y Xiong, L Chen, P Liu, T Yu, C Lin, C Yan, Y Hu… - Small, 2022 - Wiley Online Library
The treatment of diabetic wounds remains a major challenge in clinical practice, with chronic
wounds characterized by multiple drug‐resistant bacterial infections, angiopathy, and …
wounds characterized by multiple drug‐resistant bacterial infections, angiopathy, and …
Responsive multifunctional hydrogels emulating the chronic wounds healing cascade for skin repair
W Zhang, W Liu, L Long, S He, Z Wang, Y Liu… - Journal of Controlled …, 2023 - Elsevier
It remains challenging to cure chronic diabetic wounds due to its' harsh microenvironment
and poor tissue regeneration ability. At present, bacteria elimination, inflammatory response …
and poor tissue regeneration ability. At present, bacteria elimination, inflammatory response …
Bioactive injectable hydrogel dressings for bacteria-infected diabetic wound healing: a “pull–push” approach
Chronic diabetic wound healing remains a challenge due to the existence of excessive
danger molecules and bacteria in the inflammatory microenvironment. There is an urgent …
danger molecules and bacteria in the inflammatory microenvironment. There is an urgent …
A Nanozyme‐Immobilized Hydrogel with Endogenous ROS‐Scavenging and Oxygen Generation Abilities for Significantly Promoting Oxidative Diabetic Wound …
Z Li, Y Zhao, H Huang, C Zhang, H Liu… - Advanced …, 2022 - Wiley Online Library
Non‐healing wound is a common complication of diabetic patients associated with high
morbidity and mortality. Engineered therapeutic hydrogels have enviable advantages in …
morbidity and mortality. Engineered therapeutic hydrogels have enviable advantages in …
Development of a microenvironment-responsive hydrogel promoting chronically infected diabetic wound healing through sequential hemostatic, antibacterial, and …
C Guo, Y Wu, W Li, Y Wang, Q Kong - ACS Applied Materials & …, 2022 - ACS Publications
Microenvironment-responsive hydrogels present high potential in treating refractory wounds
due to their capability of on-demand drug release. In this study, a specially designed …
due to their capability of on-demand drug release. In this study, a specially designed …
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