Approximately half of all cardiovascular deaths associated with acute coronary syndrome
occur when the thin fibrous cap tissue overlying the necrotic core in a coronary vessel is …

Background: The mechanical rupture of an atheroma cap may initiate a thrombus formation,
followed by an acute coronary event and death. Several morphology and tissue composition …

While it is generally accepted that ruptures in fibrous cap atheromas cause most acute
coronary deaths, and that plaque rupture occurs in the fibrous cap at the location where the …

Increased mechanical stresses of the fibroatheroma cap tissue is a crucial risk factor on the
pathogenesis of asymptomatic coronary artery disease events. Moreover, both numerical …

Background A 'thin'fibrous cap atheroma is the typical morphological characteristic of
vulnerable plaque. Yet the very pathological studies that have provided these descriptions …

Background—Increased biomechanical stresses in the fibrous cap of atherosclerotic
plaques contribute to plaque rupture and, consequently, to thrombosis and myocardial …

Heart attacks are often caused by rupture of caps of atherosclerotic plaques in coronary
arteries. Cap rupture occurs when cap stress exceeds cap strength. We investigated the …

Background Rupture of the cap of a vulnerable plaque present in a coronary vessel may
cause myocardial infarction and death. Cap rupture occurs when the peak cap stress …

For many decades, cardiovascular calcification has been considered as a passive process,
accompanying atheroma progression, correlated with plaque burden, and apparently …

This review examines changing perspectives on the biomechanics of vulnerable plaque
rupture over the past 25 years from the first finite element analyses (FEA) showing that the …