Pharmacokinetics of coencapsulated antiretrovirals with ingestible sensors

H Liu, E Daar, Y Wang, L Siqueiros… - AIDS Research and …, 2020 - liebertpub.com
We investigated the use of a system with an ingestible sensor (Proteus Digital Health
Feedback system) coencapsulated with antiretrovirals (ARVs) to measure real-time …

Ingestible sensor system for measuring, monitoring and enhancing adherence to antiretroviral therapy: an open-label, usual care-controlled, randomised trial

H Liu, Y Wang, Y Huang, D Xiong, J Shen… - …, 2022 - thelancet.com
Summary Background Co-encapsulated antiretrovirals (ARVs) with ingestible sensor (IS)
has the capacity to monitor adherence in real-time using a sensor patch, a mobile device …

Bioequivalence of tenofovir and emtricitabine after coencapsulation with the proteus ingestible sensor

ME Ibrahim, KM Brooks… - AIDS Research and …, 2018 - liebertpub.com
Adherence to tenofovir disoproxil fumarate/emtricitabine (TDF/FTC, Truvada®) is the primary
determinant of HIV pre-exposure prophylaxis (PrEP) efficacy. Despite its importance …

Real‐time and wireless assessment of adherence to antiretroviral therapy with Co‐encapsulated ingestion sensor in HIV‐infected patients: A pilot study

ES Daar, MI Rosen, Y Wang, L Siqueiros… - Clinical and …, 2020 - Wiley Online Library
Adherence with antiretroviral therapy is important for preventing disease progression and
HIV transmission. The co‐encapsulated pill sensor system sends a signal through a …

Ingestible electronic sensors for monitoring real-time adherence to HIV pre-exposure prophylaxis and antiretroviral therapy

GR Goodman, C Vaz, H Albrechta, EW Boyer… - Current HIV/AIDS …, 2022 - Springer
Abstract Purpose of Review This review summarizes the recent advancements and future
directions of digital pill systems (DPS)—which utilize ingestible sensors to directly measure …

Bioequivalence of tenofovir component of tenofovir/rilpivirine/emtricitabine in digital pills

PR Chai, LM Pereira, GD Jambaulikar… - AIDS research and …, 2019 - liebertpub.com
Digital pills, gelatin capsules with radiofrequency transmitters activated by stomach chloride
ions, directly measure antiretroviral therapy adherence. In individuals with substance use …

Point-of-care detection of nonadherence to antiretroviral treatment for HIV-1 in resource-limited settings using drug level testing for efavirenz, lopinavir, and …

LE Hermans, M Nijhuis, HA Tempelman… - JAIDS Journal of …, 2021 - journals.lww.com
Background: Virological failure during antiretroviral treatment (ART) may indicate the
presence of drug resistance, but may also originate from nonadherence. Qualitative …

Design and delivery of real-time adherence data to men who have sex with men using antiretroviral pre-exposure prophylaxis via an ingestible electronic sensor

PR Chai, G Goodman, M Bustamante, L Mendez… - AIDS and Behavior, 2021 - Springer
Once daily tenofovir/emtricitabine when used for pre-exposure prophylaxis (PrEP) is
effective in preventing HIV acquisition but requires consistent medication adherence. The …

Crushed vs dissolved bictegravir/emtricitabine/tenofovir alafenamide

TM Johnson, CG Rivera - American Journal of Health-System …, 2023 - academic.oup.com
In a recently published paper, Rowe and colleagues1 describe a case of an acutely
hospitalized cisgender male recently diagnosed as a person living with HIV (PWH) who did …

Enzymatic assay for rapid measurement of antiretroviral drug levels

AO Olanrewaju, BP Sullivan, JY Zhang, AT Bender… - ACS …, 2020 - ACS Publications
Poor adherence to pre-exposure prophylaxis (PrEP) and antiretroviral therapy (ART) can
lead to human immunodeficiency virus (HIV) acquisition and emergence of drug-resistant …