Counterregulation between thymic stromal lymphopoietin–and IL-23–driven immune axes shapes skin inflammation in mice with epidermal barrier defects
J Li, JM Leyva-Castillo, P Hener, A Eisenmann… - Journal of Allergy and …, 2016 - Elsevier
Background Epidermal barrier dysfunction has been recognized as a critical factor in the
initiation and exacerbation of skin inflammation, particularly in patients with atopic dermatitis …
initiation and exacerbation of skin inflammation, particularly in patients with atopic dermatitis …
Prostaglandin E2 (PGE2)–EP2 signaling negatively regulates murine atopic dermatitis–like skin inflammation by suppressing thymic stromal lymphopoietin expression
Background Atopic dermatitis (AD) is a common and chronic inflammatory skin disease of
type 2 immunity. Keratinocyte-derived cytokines, including thymic stromal lymphopoietin …
type 2 immunity. Keratinocyte-derived cytokines, including thymic stromal lymphopoietin …
IL‐1β induces thymic stromal lymphopoietin and an atopic dermatitis‐like phenotype in reconstructed healthy human epidermis
M Bernard, C Carrasco, L Laoubi… - The Journal of …, 2017 - Wiley Online Library
Atopic dermatitis (AD) is a common skin inflammatory disease characterized by the
production of thymic stromal lymphopoietin (TSLP) and marked TH2 polarization. Recent …
production of thymic stromal lymphopoietin (TSLP) and marked TH2 polarization. Recent …
[HTML][HTML] TSLP down-regulates S100A7 and ß-defensin 2 via the JAK2/STAT3-dependent mechanism
Elevated T-helper type 2 cytokines in atopic skin, such as IL-4 and IL-13, were thought to be
responsible for an impaired expression of antimicrobial proteins, which may contribute to the …
responsible for an impaired expression of antimicrobial proteins, which may contribute to the …
Thymic stromal lymphopoietin‐induced interleukin‐17 A is involved in the development of I g E‐mediated atopic dermatitis‐like skin lesions in mice
Atopic dermatitis (AD) is a chronic inflammatory skin disease associated with elevated levels
of allergen‐specific IgE. Although thymic stromal lymphopoietin (TSLP) and interleukin‐17A …
of allergen‐specific IgE. Although thymic stromal lymphopoietin (TSLP) and interleukin‐17A …
Thymic stromal lymphopoietin, skin barrier dysfunction, and the atopic march
SF Ziegler - Annals of Allergy, Asthma & Immunology, 2021 - Elsevier
Objective Atopic dermatitis often precedes the development of other atopic diseases, and
the atopic march describes this temporal relationship in the natural history of these diseases …
the atopic march describes this temporal relationship in the natural history of these diseases …
IL-4 impairs wound healing potential in the skin by repressing fibronectin expression
APM Serezani, G Bozdogan, S Sehra, D Walsh… - Journal of Allergy and …, 2017 - Elsevier
Background Atopic dermatitis (AD) is characterized by intense pruritis and is a common
childhood inflammatory disease. Many factors are known to affect AD development …
childhood inflammatory disease. Many factors are known to affect AD development …
Thymic stromal lymphopoietin is a critical mediator of IL‐13‐driven allergic inflammation
M Miyata, Y Nakamura, N Shimokawa… - European journal of …, 2009 - Wiley Online Library
Both thymic stromal lymphopoietin (TSLP) and IL‐13 are essential cytokines for the
development of allergic inflammation. However, a causal link between TSLP and IL‐13 has …
development of allergic inflammation. However, a causal link between TSLP and IL‐13 has …
Keratin defects trigger the itch-inducing cytokine thymic stromal lymphopoietin through amphiregulin–epidermal growth factor receptor signaling
A Scheffschick, D Kiritsi, TM Magin - Journal of Allergy and Clinical …, 2019 - jacionline.org
REFERENCES 1. Georas SN, Rezaee F. Epithelial barrier function: at the front line of
asthma immunology and allergic airway inflammation. J Allergy Clin Immunol 2014; 134 …
asthma immunology and allergic airway inflammation. J Allergy Clin Immunol 2014; 134 …
Increased Th2 activity and diminished skin barrier function cooperate in allergic skin inflammation
S Sehra, P Krishnamurthy, B Koh… - European journal of …, 2016 - Wiley Online Library
Atopic dermatitis (AD) is a chronic inflammatory skin disease induced by a complex
interaction between susceptibility genes encoding skin barrier components and …
interaction between susceptibility genes encoding skin barrier components and …