The critical 8p22 tumor suppressor deleted in liver cancer 1 (DLC1) is frequently inactivated
by aberrant CpG methylation and/or genetic deletion and implicated in tumorigeneses of …

Identification of tumor suppressor genes (TSG) silenced by methylation uncovers
mechanisms of tumorigenesis and identifies new epigenetic tumor markers for early cancer …

The deleted in liver cancer (DLC-1) gene at chromosome 8p21–22 is altered mainly by
genomic deletion or aberrant promoter methylation in a large number of human cancers …

The human DLC-1 (deleted in liver cancer 1) gene was cloned from a primary human
hepatocellular carcinoma (HCC) and mapped to the chromosome 8p21–22 region …

The DLC-1 gene, located at the human chromosome region 8p22, behaves like a tumor
suppressor gene and is frequently deleted in diverse tumors. The deletion of 8p22 is not an …

Epigenetic mechanisms involving DNA methylation and chromatin remodeling are important
in silencing tumor suppressor genes (TSG) in various malignancies, including renal cell …

DLC-1 (deleted in liver cancer) gene is frequently deleted in hepatocellular carcinoma.
However, little is known about the genetic status and the expression of this gene in gastric …

The chromosome region 8p12-p22 shows frequent allelic loss in many neoplasms, including
breast cancer (BC). The DLC-1 gene, located on 8p21-p22, might be a candidate tumor …

Aberrant methylation of CpG islands within the promoter regions of tumor suppressor or
cancer-related genes is a common mechanism leading to the silencing of gene expression …

DLC1 (deleted in liver cancer-1) is a new candidate tumor suppressor gene, which is
inactive in various types of human cancers including colon cancer. To study the function of …