Single Cell Transcriptomics of Myeloid Cells in Black Americans with Multiple Sclerosis (P2-3.009)

J Bingen, L Clark, C Wright, F Xu, M Carrithers - 2023 - AAN Enterprises
Objective: Identify myeloid cell subsets from peripheral blood and monocyte-derived
macrophages associated with MS in Black Americans. Background: Prior work in a cohort of …

Identifying alterations in RNA metabolism and translation dynamics of oligodendrocytes in Alzheimer's disease

AM Gaminde Blasco - 2023 - addi.ehu.es
More than half of the human brain volume is made up of white matter (WM), which enables
fast and efficient nerve conduction, required for a proper cognitive function in the central …

[引用][C] Single nuclei transcriptomics of human white matter oligodendroglia in multiple sclerosis

E Agirre, S Jakel, AM Falcao… - MULTIPLE …, 2019 - … LTD 1 OLIVERS YARD, 55 CITY …

Brain macrophages acquire distinct transcriptomes in multiple sclerosis lesions and normal appearing white matter

A Miedema, E Gerrits, N Brouwer, Q Jiang… - Acta neuropathologica …, 2022 - Springer
Multiple sclerosis (MS) is a disease of the central nervous system that is characterized by
inflammation and focal areas of demyelination, ultimately resulting in axonal degradation …

Single-Cell Genomics Reveals Spatial and Stage-Associated Diversity in Multiple Sclerosis (P2. 2-070)

L Schirmer, D Velmeshev, D Jung, S Vistnes… - 2019 - AAN Enterprises
Objective: To dissect cellular heterogeneity and understand molecular changes in
inflammatory cells, neurons and glial cell types by single-cell genomics of MS and control …

Time to revisit oligodendrocytes in multiple sclerosis

KA Nave, H Ehrenreich - Nature medicine, 2019 - nature.com
Time to revisit oligodendrocytes in multiple sclerosis | Nature Medicine Skip to main content
Thank you for visiting nature.com. You are using a browser version with limited support for …

[PDF][PDF] Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis

A Mendanha Falcão, D van Bruggen, S Marques… - 2019 - core.ac.uk
Edinburgh Research Explorer Page 1 Edinburgh Research Explorer Disease-specific
oligodendrocyte lineage cells arise in multiple sclerosis Citation for published version …

Comparing RNA‐sequencing datasets from astrocytes, oligodendrocytes, and microglia in multiple sclerosis identifies novel dysregulated genes relevant to …

SS Drake, A Zaman, T Simas… - WIREs Mechanisms of …, 2023 - Wiley Online Library
Central nervous system (CNS) inflammation is a key factor in multiple sclerosis (MS).
Invasion of peripheral immune cells into the CNS resulting from an unknown signal or …

[HTML][HTML] High-resolution transcriptomic and proteomic profiling of heterogeneity of brain-derived microglia in multiple sclerosis

A Miedema, MHC Wijering, BJL Eggen… - Frontiers in molecular …, 2020 - frontiersin.org
Microglia are important for central nervous system (CNS) homeostasis and first to respond to
tissue damage and perturbations. Microglia are heterogeneous cells; in case of pathology …

[PDF][PDF] 2 High-resolution transcriptomic and proteomic profiling of microglia heterogeneity in MS

A Miedema, MHC Wijering, BJL Eggen… - Mosaic of glia in …, 2023 - research.rug.nl
Microglia are important for central nervous system (CNS) homeostasis and first to respond to
tissue damage and perturbations. Microglia are heterogeneous cells; in case of pathology …