AKT1 and neurocognition in schizophrenia [corrected][published erratum appears in AUST NZ J PSYCHIATRY 2009 Oct; 43 (10): 983].
AP Pinheiro, RS Keefe, T Skelly… - Australian & New …, 2007 - search.ebscohost.com
OBJECTIVE: Previous research has shown conflicting results for the significance of five v-akt
murine thymoma viral oncogene homolog 1 (AKT1) single-nucleotide polymorphisms …
murine thymoma viral oncogene homolog 1 (AKT1) single-nucleotide polymorphisms …
AKT-2 and cognition: AKT-2 mutant mice exhibit behavioural phenotype relevant to schizophrenia
S Palumbo, J Amanda - BIOLOGICAL PSYCHIATRY, 2012 - arpi.unipi.it
Background: The AKT family consists of three highly homologous kinases, AKT-1, AKT-2
and AKT-3, encoded by different genes. Polymorphic variation in AKT-1 has been …
and AKT-3, encoded by different genes. Polymorphic variation in AKT-1 has been …
AKT-2 Heterozygous Mice Exhibit a Unique Behavioral Phenotype Relevant to Schizophrenia
Background: The AKT family consists of three highly homologous kinases, AKT-1, AKT-2
and AKT-3, encoded by different genes. Polymorphic variation in AKT-1 has been …
and AKT-3, encoded by different genes. Polymorphic variation in AKT-1 has been …
[HTML][HTML] Epistatic interactions of AKT1 on human medial temporal lobe biology and pharmacogenetic implications
AKT1 controls important processes in medial temporal lobe (MTL) development and
plasticity, but the impact of human genetic variation in AKT1 on these processes is not …
plasticity, but the impact of human genetic variation in AKT1 on these processes is not …
[HTML][HTML] PKBγ/AKT3 loss-of-function causes learning and memory deficits and deregulation of AKT/mTORC2 signaling: Relevance for schizophrenia
Psychiatric genetic studies have identified genome-wide significant loci for schizophrenia.
The AKT3/1q44 locus is a principal risk region and gene-network analyses identify AKT3 …
The AKT3/1q44 locus is a principal risk region and gene-network analyses identify AKT3 …
AKT1 and Neurocognition in Schizophrenia
AP Pinheiro, RSE Keefe, T Skelly… - Australian & New …, 2007 - journals.sagepub.com
Objective: Previous research has shown conflicting results for the significance of five v-akt
murine thymoma viral oncogene homolog 1 (AKT1) single-nucleotide polymorphisms …
murine thymoma viral oncogene homolog 1 (AKT1) single-nucleotide polymorphisms …
[HTML][HTML] Genetic variation in AKT1 is linked to dopamine-associated prefrontal cortical structure and function in humans
AKT1-dependent molecular pathways control diverse aspects of cellular development and
adaptation, including interactions with neuronal dopaminergic signaling. If AKT1 has an …
adaptation, including interactions with neuronal dopaminergic signaling. If AKT1 has an …
Akt1 deficiency affects neuronal morphology and predisposes to abnormalities in prefrontal cortex functioning
WS Lai, B Xu, KGC Westphal… - Proceedings of the …, 2006 - National Acad Sciences
There is accumulating evidence that AKT signaling plays a role in the pathogenesis of
schizophrenia. We asked whether Akt1 deficiency in mice results in structural and functional …
schizophrenia. We asked whether Akt1 deficiency in mice results in structural and functional …
AKT1 is associated with schizophrenia across multiple symptom dimensions in the Irish study of high density schizophrenia families
BACKGROUND: The phosphatidylinositol 3-kinase (PI3K)-AKT signal transduction pathway
is critical to cell growth and survival. In vitro functional studies indicate that the candidate …
is critical to cell growth and survival. In vitro functional studies indicate that the candidate …
Failure to support a genetic contribution of AKT1 polymorphisms and altered AKT signaling in schizophrenia
M Ide, T Ohnishi, M Murayama… - Journal of …, 2006 - Wiley Online Library
The protein kinase v‐akt murine thymoma viral oncogene homolog (AKT) gene family
comprises three human homologs that phosphorylate and inactivate glycogen synthase …
comprises three human homologs that phosphorylate and inactivate glycogen synthase …