Physico-genetics of morphogenesis: the hybrid nature of developmental mechanisms
SA Newman - Towards a theory of development, 2014 - books.google.com
Like all parcels of matter, embryos are subject to physical forces and effects relevant to their
composition and scale (Forgacs & Newman, 2005). They thus bear the morphological …
composition and scale (Forgacs & Newman, 2005). They thus bear the morphological …
On the evolution of morphogenetic models: mechano‐chemical interactions and an integrated view of cell differentiation, growth, pattern formation and morphogenesis
S Urdy - Biological Reviews, 2012 - Wiley Online Library
In the 1950s, embryology was conceptualized as four relatively independent problems: cell
differentiation, growth, pattern formation and morphogenesis. The mechanisms underlying …
differentiation, growth, pattern formation and morphogenesis. The mechanisms underlying …
[PDF][PDF] Developmental mechanisms: putting genes in their place
SA Newman - Journal of biosciences, 2002 - ias.ac.in
Developmental biologists study changes in shape and form of embryonic tissues, the
differentiation of their constituent cell types, the patterned arrangement of the resulting cells …
differentiation of their constituent cell types, the patterned arrangement of the resulting cells …
'Generic'physical mechanisms of morphogenesis and pattern formation
SA Newman, WD Comper - Development, 1990 - journals.biologists.com
The role of 'generic'physical mechanisms in morphogenesis and pattern formation of tissues
is considered. Generic mechanisms are defined as those physical processes that are …
is considered. Generic mechanisms are defined as those physical processes that are …
Generic physical mechanisms of morphogenesis and pattern formation as determinants in the evolution of multicellular organization
SA Newman - Journal of biosciences, 1992 - Springer
Early embryos of metazoan species are subject to the same set of physical forces and
interactions as any small parcels of semi-solid material, living or nonliving. It is proposed that …
interactions as any small parcels of semi-solid material, living or nonliving. It is proposed that …
Morphogenesis as a macroscopic self-organizing process
LV Beloussov - Biosystems, 2012 - Elsevier
We start from reviewing different epistemological constructions used for explaining
morphogenesis. Among them, we explore the explanatory power of a law-centered …
morphogenesis. Among them, we explore the explanatory power of a law-centered …
Inherency and homomorphy in the evolution of development
SA Newman - Current Opinion in Genetics & Development, 2019 - Elsevier
Organismal development occurs when expression of certain genes leads to the mobilization
of physical forces and effects that shape and pattern multicellular clusters. All materials …
of physical forces and effects that shape and pattern multicellular clusters. All materials …
Coupling of growth, differentiation and morphogenesis: an integrated approach to design in embryogenesis
There is increasing evidence that cellular differentiation is induced by mechanical stresses,
either shear (dislocation of haemangioblasts into erythrocytes and endothelial cells, arterial …
either shear (dislocation of haemangioblasts into erythrocytes and endothelial cells, arterial …
Physico-genetic determinants in the evolution of development
SA Newman - Science, 2012 - science.org
Animal bodies and the embryos that generate them exhibit an assortment of stereotypic
morphological motifs that first appeared more than half a billion years ago. During …
morphological motifs that first appeared more than half a billion years ago. During …
Physical determinants in the emergence and inheritance of multicellular form
SA Newman, M Linde-Medina - Biological Theory, 2013 - Springer
We argue that the physics of complex materials and self-organizing processes should be
made central to the biology of form. Rather than being encoded in genes, form emerges …
made central to the biology of form. Rather than being encoded in genes, form emerges …