COVID-19–related genes in sputum cells in asthma. Relationship to demographic features and corticosteroids

MC Peters, S Sajuthi, P Deford… - American journal of …, 2020 - atsjournals.org
Rationale: Coronavirus disease (COVID-19) is caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). ACE2 (angiotensin-converting enzyme 2), and …

[HTML][HTML] COVID-19, asthma, and inhaled corticosteroids: another beneficial effect of inhaled corticosteroids?

T Maes, K Bracke, GG Brusselle - American Journal of Respiratory …, 2020 - atsjournals.org
Coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2), has become a real pandemic. After a median incubation period of 5 days …

[HTML][HTML] Airways expression of SARS-CoV-2 receptor, ACE2, and TMPRSS2 is lower in children than adults and increases with smoking and COPD

NS Sharif-Askari, FS Sharif-Askari, M Alabed… - … Therapy Methods & …, 2020 - cell.com
It has been reported that angiotensin-converting enzyme 2 (ACE2) and transmembrane
serine protease 2 (TMPRSS2) are the main cell entry proteins for severe acute respiratory …

ACE2, TMPRSS2, and furin gene expression in the airways of people with asthma—implications for COVID-19

P Bradding, M Richardson, TSC Hinks… - Journal of Allergy and …, 2020 - jacionline.org
Bénite, dthe National Referee Centre for Rheumatic and AutoImmune and Systemic
diseases in childrEn (RAISE), and eLyon Immunopathology Federation LIFE, Hospices …

Distinct effects of asthma and COPD comorbidity on disease expression and outcome in patients with COVID‐19

J Song, M Zeng, H Wang, C Qin, HY Hou, ZY Sun… - Allergy, 2021 - Wiley Online Library
Background The impacts of chronic airway diseases on coronavirus disease 2019 (COVID‐
19) are far from understood. Objective To explore the influence of asthma and chronic …

Expression of the SARS-CoV-2 ACE2 Receptor in the Human Airway Epithelium

H Zhang, MR Rostami, PL Leopold… - American journal of …, 2020 - atsjournals.org
Rationale: Infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) causes coronavirus disease (COVID-19), a predominantly respiratory illness. The first …

Type 2 inflammation modulates ACE2 and TMPRSS2 in airway epithelial cells

H Kimura, D Francisco, M Conway, FD Martinez… - Journal of Allergy and …, 2020 - Elsevier
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
dramatically changed our world, country, communities, and families. There is controversy …

Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue

JA Aguiar, BJM Tremblay, MJ Mansfield… - European …, 2020 - Eur Respiratory Soc
In December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
emerged, causing the coronavirus disease 2019 (COVID-19) pandemic. SARS-CoV, the …

Expression of SARS-CoV-2 receptor ACE2 and coincident host response signature varies by asthma inflammatory phenotype

M Camiolo, M Gauthier, N Kaminski, A Ray… - Journal of Allergy and …, 2020 - Elsevier
Background More than 300 million people carry a diagnosis of asthma, with data to suggest
that they are at a higher risk for infection or adverse outcomes from severe acute respiratory …

[HTML][HTML] Tobacco smoking increases the lung gene expression of ACE2, the receptor of SARS-CoV-2

G Cai, Y Bossé, F Xiao, F Kheradmand… - American journal of …, 2020 - atsjournals.org
Methods We evaluated a comprehensive set of transcriptomic data sets to investigate the
associations of smoking with ACE2, FURIN, and TMPRSS2 gene expression in lung tissues …