The pitfalls of proteomics experiments without the correct use of bioinformatics tools
The elucidation of the entire genomic sequence of various organisms, from viruses to
complex metazoans, most recently man, is undoubtedly the greatest triumph of molecular …
complex metazoans, most recently man, is undoubtedly the greatest triumph of molecular …
Interaction proteomics
The term proteome is traditionally associated with the identification of a large number of
proteins within complex mixtures originating from a given organelle, cell or even organism …
proteins within complex mixtures originating from a given organelle, cell or even organism …
Protein–protein interaction maps: a lead towards cellular functions
P Legrain, J Wojcik, JM Gauthier - Trends in genetics, 2001 - cell.com
The availability of complete genome sequences now permits the development of tools for
functional biology on a proteomic scale. Several experimental approaches or in silico …
functional biology on a proteomic scale. Several experimental approaches or in silico …
The post‐genomic era of interactive proteomics: Facts and perspectives
D Auerbach, S Thaminy, MO Hottiger, I Stagljar - Proteomics, 2002 - Wiley Online Library
The availability of completed genome sequences of several eukaryotic and prokaryotic
species has shifted the focus towards the identification and characterization of all gene …
species has shifted the focus towards the identification and characterization of all gene …
From classical to new generation approaches: An excursus of-omics methods for investigation of protein-protein interaction networks
I Iacobucci, V Monaco, F Cozzolino, M Monti - Journal of proteomics, 2021 - Elsevier
Functional Proteomics aims to the identification of in vivo protein-protein interaction (PPI) in
order to piece together protein complexes, and therefore, cell pathways involved in …
order to piece together protein complexes, and therefore, cell pathways involved in …
Integrating a functional proteomic approach into the target discovery process
F Colland, L Daviet - Biochimie, 2004 - Elsevier
Functional proteomics is a promising technique for the rational identification of novel
therapeutic targets by elucidation of the function of newly identified proteins in disease …
therapeutic targets by elucidation of the function of newly identified proteins in disease …
Identifying novel protein interactions: Proteomic methods, optimisation approaches and data analysis pipelines
The technological revolution in high-throughput nucleic acid and protein analysis in the last
15 years has launched the field of 'omics' and led to great advances in our understanding of …
15 years has launched the field of 'omics' and led to great advances in our understanding of …
Twenty years of protein interaction studies for biological function deciphering
P Legrain, JC Rain - Journal of proteomics, 2014 - Elsevier
Intensive methodological developments and technology innovation have been devoted to
protein–protein interaction studies over 20 years. Genetic indirect assays and sophisticated …
protein–protein interaction studies over 20 years. Genetic indirect assays and sophisticated …
[HTML][HTML] Categorizing biases in high-confidence high-throughput protein-protein interaction data sets
X Yu, J Ivanic, V Memišević, A Wallqvist… - Molecular & Cellular …, 2011 - ASBMB
We characterized and evaluated the functional attributes of three yeast high-confidence
protein-protein interaction data sets derived from affinity purification/mass spectrometry …
protein-protein interaction data sets derived from affinity purification/mass spectrometry …
Bioinformatics challenges in proteomics
CC Englbrecht, A Facius - Combinatorial chemistry & high …, 2005 - ingentaconnect.com
A little after the genomic revolution had been celebrated, it seemed as if a competition
began to found new-omics disciplines that ultimately all have the same goal, the …
began to found new-omics disciplines that ultimately all have the same goal, the …