Immunotherapy for colorectal cancer: where are we heading?

D Basile, SK Garattini, M Bonotto… - Expert opinion on …, 2017 - Taylor & Francis
Introduction: In the last few years, significant advances in molecular biology have provided
new therapeutic options for colorectal cancer (CRC). The development of new drugs that …

[HTML][HTML] Immunotherapy in human colorectal cancer: challenges and prospective

X Sun, J Suo, J Yan - World Journal of Gastroenterology, 2016 - ncbi.nlm.nih.gov
Human colorectal cancer (CRC) is the third most commonly diagnosed malignancies and
the prognosis for patients with recurrent or metastatic disease is extremely poor. Although …

[HTML][HTML] Immunotherapy in colorectal cancer: current achievements and future perspective

A Fan, B Wang, X Wang, Y Nie, D Fan… - International Journal of …, 2021 - ncbi.nlm.nih.gov
Following dramatic success in many types of advanced solid tumors, interest in
immunotherapy for the treatment of colorectal cancer (CRC) is increasingly growing. Given …

Immunotherapy for colorectal cancer: Rational strategies and novel therapeutic progress

F Rastin, H Javid, MA Oryani, N Rezagholinejad… - International …, 2024 - Elsevier
There are increasing incidences and mortality rates for colorectal cancer in the world. It is
common for chemotherapy and radiation given to patients with colorectal cancer to cause …

The potential role of immunotherapy to treat colorectal cancer

M Amin, AC Lockhart - Expert opinion on investigational drugs, 2015 - Taylor & Francis
Introduction: Colorectal cancer (CRC) is the fourth most common cancer and the second
leading cause of cancer-related death worldwide. Surgery, chemotherapy, radiation therapy …

[HTML][HTML] Is the combination of immunotherapy with conventional chemotherapy the key to increase the efficacy of colorectal cancer treatment?

JE Olguin, MG Mendoza-Rodriguez… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is among the most prevalent and deadly neoplasms worldwide.
According to GLOBOCAN predictions, its incidence will increase from 1.15 million CRC …

Checkpoints and beyond–immunotherapy in colorectal cancer

T Gutting, E Burgermeister, N Härtel… - Seminars in Cancer …, 2019 - Elsevier
Immunotherapy is the latest revolution in cancer therapy. It continues to show impressive
results in malignancies like melanoma and others. At least so far, effects are modest in …

Can immunotherapy reinforce chemotherapy efficacy? a new perspective on colorectal cancer treatment

X He, H Lan, K Jin, F Liu - Frontiers in Immunology, 2023 - frontiersin.org
As one of the main threats to human life (the fourth most dangerous and prevalent cancer),
colorectal cancer affects many people yearly, decreases patients' quality of life, and causes …

[HTML][HTML] The emerging role of immunotherapy in colorectal cancer

D Lynch, A Murphy - Annals of translational medicine, 2016 - ncbi.nlm.nih.gov
Modulation of the interaction between the immune system and the tumor microenvironment
has long been a target of cancer research, including colorectal cancer (CRC). Approaches …

Revolutionizing the landscape of colorectal cancer treatment: the potential role of immune checkpoint inhibitors

MF Tolba - International journal of cancer, 2020 - Wiley Online Library
Colorectal cancer (CRC) represents the third cause of cancer‐related mortalities worldwide.
The progression of CRC to the metastatic phase significantly compromises the overall …