This work illustrates a new role for the membranotropic peptide gH625 and its derivative
gH625-GCGKKK in impairing formation of polymicrobial biofilms. Mixed biofilms composed …

The antibiofilm activity of a gH625 analogue was investigated to determine the in vitro
inhibition and eradication of a dual-species biofilm of Candida albicans and Klebsiella …

Biofilm-related infections account for at least 65% of all human infections, but there are no
available antimicrobials that specifically target biofilms. Their elimination by available …

Biofilms lead to approximately 65% of infections, and these infections are hard to treat. Thus,
it is crucial to identify effective antibiofilm agents with low cytotoxicity. Peptides with …

Staphylococci, notably biofilm-forming Staphylococcus epidermidis, have been recognized
as global nosocomial pathogens in medical device-related infections. Their potential to …

Biofilm formation poses an important clinical trouble due to resistance to antimicrobial
agents; therefore, there is an urgent demand for new antibiofilm strategies that focus on the …

Biofilms cause up to 80% of infections and are difficult to treat due to their substantial
multidrug resistance compared to their planktonic counterparts. Based on the observation …

The great clinical significance of biofilm-associated infections and their inherent
recalcitrance to antibiotic treatment urgently demand the development of novel antibiofilm …

Surface colonization and the formation of biofilms by microbes are well acknowledged.
Communities of microorganisms are coated in these biofilms, which frequently include …

In vitro activity against methicillin-resistant Staphylococcus aureus (MRSA) and
Staphylococcus epidermidis biofilm producers from blood cultures of patients with prosthetic …