Incidence of hepatotoxicity caused by the broad spectrum antibiotic combination amoxicillin-
clavulanic acid (Co-amoxyclav) has been increasingly recognized and the mechanism of …

Ceftriaxone is a broad-spectrum semisynthetic cephalosporin antibiotic that causes partial
damage in the liver manifested by transient elevation in some biochemical parameters. In …

AIM: To investigate the effects of ursodeoxycholic acid (UDCA) on chenodeoxycholic acid
(CDCA)-induced liver injury in hamsters, and to elucidate a correlation between liver injury …

Purpose: The aim of this study was to evaluate the role of an antioxidant factor in the
hepatoprotective effect of ursodeoxycholic acid (UDCA) in rat alcoholic steatohepatitis …

Aim: The data on the beneficial effect of ursodeoxycholic acid (UDCA) in non‐alcoholic
steatohepatitis (NASH) are controversial. The difference of opinion is connected with UDCA …

Ursodeoxycholic acid (UDCA) is widely used for the therapy of liver dysfunction. In this
study, we investigated the protective effect of UDCA in concanavalin A-induced mouse liver …

Accumulation of hydrophobic bile acids (BAs) during cholestasis plays an important role in
apoptosis initiation as well as oxidative stress increase in liver cells. Ursodeoxycholic acid …

The available conventional remedies for the treatment of drug-induced liver diseases are
highly inadequate and possess serious adverse effects; therefore, the development of new …

The therapeutic benefit of ursodeoxycholic acid (UDCA) in treating cholestatic liver disease
is globally recognized. It is generally accepted that the mechanism of action of UDCA can be …

Clinical studies have shown that several classes of antibiotics are evidenced in drug
induced liver injury. The combination of amoxicillin with clavulanic acid is commonly cited in …