Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome
A Kotzsch, J Nickel, A Seher, K Heinecke… - Journal of Biological …, 2008 - ASBMB
Bone morphogenetic proteins regulate many developmental processes during
embryogenesis as well as tissue homeostasis in the adult. Signaling of bone morphogenetic …
embryogenesis as well as tissue homeostasis in the adult. Signaling of bone morphogenetic …
The mode of bone morphogenetic protein (BMP) receptor oligomerization determines different BMP-2 signaling pathways
Bone morphogenetic proteins (BMPs) are multifunctional proteins regulating cell growth,
differentiation, and apoptosis. BMP-2 signals via two types of receptors (BRI and BRII) that …
differentiation, and apoptosis. BMP-2 signals via two types of receptors (BRI and BRII) that …
[HTML][HTML] Isolation of recombinant BMP receptor IA ectodomain and its 2: 1 complex with BMP-2
T Kirsch, J Nickel, W Sebald - FEBS letters, 2000 - Elsevier
Bone morphogenetic protein-2 (BMP-2) is a member of the transforming growth factor β
superfamily which induces bone formation and regeneration, and important steps during …
superfamily which induces bone formation and regeneration, and important steps during …
Bone morphogenetic protein receptors
H Yamashita, P Ten Dijke, CH Heldin, K Miyazono - Bone, 1996 - Elsevier
Bone morphogenetic proteins (BMPs) were originally identified as proteins that induce bone
formation at extraskeletal sites (reviewed in Reddi33). More recent studies have shown that …
formation at extraskeletal sites (reviewed in Reddi33). More recent studies have shown that …
Receptor oligomerization and beyond: a case study in bone morphogenetic proteins
K Heinecke, A Seher, W Schmitz, TD Mueller… - BMC biology, 2009 - Springer
Background Transforming growth factor (TGF) β superfamily members transduce signals by
oligomerizing two classes of serine/threonine kinase receptors, termed type I and type II. In …
oligomerizing two classes of serine/threonine kinase receptors, termed type I and type II. In …
Interaction of the BMPR-IA tumor suppressor with a developmentally relevant splicing factor
TG Nishanian, T Waldman - Biochemical and biophysical research …, 2004 - Elsevier
Inactivation of bone morphogenetic protein signaling via mutation of the BMPR-IA TGF-β
superfamily type I receptor causes familial juvenile polyposis, an inherited gastrointestinal …
superfamily type I receptor causes familial juvenile polyposis, an inherited gastrointestinal …
Interaction between soluble type I receptor for bone morphogenetic protein and bone morphogenetic protein-4
T Natsume, S Tomita, S Iemura, N Kinto… - Journal of Biological …, 1997 - ASBMB
Bone morphogenetic proteins (BMPs) are multifunctional proteins that comprise the largest
subfamily of the transforming growth factor-β. These proteins bind to types I and II …
subfamily of the transforming growth factor-β. These proteins bind to types I and II …
BMP-3 and BMP-6 Structures Illuminate the Nature of Binding Specificity with Receptors,
GP Allendorph, MJ Isaacs, Y Kawakami… - Biochemistry, 2007 - ACS Publications
Bone morphogenetic proteins (BMPs) are extracellular messenger ligands involved in
controlling a wide array of developmental and intercellular signaling processes. To initiate …
controlling a wide array of developmental and intercellular signaling processes. To initiate …
Chromosomal localization of three human genes encoding bone morphogenetic protein receptors
AK Åström, D Jin, T Imamura, E Röijer… - Mammalian …, 1999 - Springer
Bone morphogenetic proteins (BMPs) are members of the TGF-β superfamily that play a
pivotal role in bone formation during embryogenesis and fracture repair. BMP signaling …
pivotal role in bone formation during embryogenesis and fracture repair. BMP signaling …
Identification of a Human Type II Receptor for Bone Morphogenetic Protein-4 That Forms Differential Heteromeric Complexes with Bone Morphogenetic Protein Type I …
T Nohno, T Ishikawa, T Saito, K Hosokawa… - Journal of Biological …, 1995 - ASBMB
Bone morphogenetic proteins (BMPs) comprise the largest subfamily of TGF-β-related
ligands and are known to bind to type I and type II receptor serine/threonine kinases …
ligands and are known to bind to type I and type II receptor serine/threonine kinases …