Initiation of antiretroviral therapy in early asymptomatic HIV infection.

JD Lundgren, AG Babiker, F Gordin… - The New England …, 2015 - europepmc.org
Background Data from randomized trials are lacking on the benefits and risks of initiating
antiretroviral therapy in patients with asymptomatic human immunodeficiency virus (HIV) …

[HTML][HTML] Initiation of antiretroviral therapy in early asymptomatic HIV infection

Insight Start Study Group - New England Journal of Medicine, 2015 - Mass Medical Soc
Background Data from randomized trials are lacking on the benefits and risks of initiating
antiretroviral therapy in patients with asymptomatic human immunodeficiency virus (HIV) …

[HTML][HTML] Effect of early versus deferred antiretroviral therapy for HIV on survival

MM Kitahata, SJ Gange, AG Abraham… - … England Journal of …, 2009 - Mass Medical Soc
Background The optimal time for the initiation of antiretroviral therapy for asymptomatic
patients with human immunodeficiency virus (HIV) infection is uncertain. Methods We …

Effects of early versus delayed initiation of antiretroviral treatment on clinical outcomes of HIV-1 infection: results from the phase 3 HPTN 052 randomised controlled …

B Grinsztejn, MC Hosseinipour, HJ Ribaudo… - The Lancet infectious …, 2014 - thelancet.com
Background Use of antiretroviral treatment for HIV-1 infection has decreased AIDS-related
morbidity and mortality and prevents sexual transmission of HIV-1. However, the best time to …

Early initiation of antiretroviral therapy in HIV-infected adults and adolescents: a systematic review

A Anglemyer, GW Rutherford, PJ Easterbrook… - Aids, 2014 - journals.lww.com
Objectives: The objective of this review was to update evidence on when to initiate
antiretroviral therapy (ART) to inform revision of the 2013 WHO guidelines for ART in low …

[HTML][HTML] Initiating antiretroviral therapy for HIV at a patient's first clinic visit: the RapIT randomized controlled trial

S Rosen, M Maskew, MP Fox, C Nyoni… - PLoS …, 2016 - journals.plos.org
Background High rates of patient attrition from care between HIV testing and antiretroviral
therapy (ART) initiation have been documented in sub-Saharan Africa, contributing to …

[HTML][HTML] Early versus standard antiretroviral therapy for HIV-infected adults in Haiti

P Severe, MA Jean Juste, A Ambroise… - … England Journal of …, 2010 - Mass Medical Soc
Background For adults with human immunodeficiency virus (HIV) infection who have CD4+
T-cell counts that are greater than 200 and less than 350 per cubic millimeter and who live in …

Association of initial CD4 cell count and viral load with response to highly active antiretroviral therapy

RE Chaisson, JC Keruly, RD Moore - Jama, 2000 - jamanetwork.com
Methods We retrospectively compared the outcomes of starting highly active antiretroviral
therapy at varying CD4 cell counts and viral loads in a clinical cohort of HIV-infected patients …

Improved outcomes with earlier initiation of highly active antiretroviral therapy among human immunodeficiency virus–infected patients who achieve durable virologic …

TR Sterling, RE Chaisson, J Keruly… - The Journal of …, 2003 - academic.oup.com
On the basis of studies with relatively short follow-up, treatment guidelines currently
recommend that highly active antiretroviral therapy (HAART) be initiated in asymptomatic …

[HTML][HTML] Timing of initiation of antiretroviral therapy in AIDS-free HIV-1-infected patients: a collaborative analysis of 18 HIV cohort studies

When To Start Consortium - The Lancet, 2009 - Elsevier
BACKGROUND: The CD4 cell count at which combination antiretroviral therapy should be
started is a central, unresolved issue in the care of HIV-1-infected patients. In the absence of …