Relationship between atheroma regression and change in lumen size after infusion of apolipoprotein AI Milano

SJ Nicholls, EM Tuzcu, I Sipahi, P Schoenhagen… - Journal of the American …, 2006 - jacc.org
Objectives: The aim of this study was to determine the relationship between atheroma
regression and arterial wall remodeling. Background: Infusion of reconstituted high-density …

Rapid Change in Plaque Size, Composition, and Molecular Footprint After Recombinant Apolipoprotein AIMilano (ETC-216) Administration: Magnetic Resonance …

B Ibanez, G Vilahur, G Cimmino, WS Speidl… - Journal of the American …, 2008 - jacc.org
Objectives: This study sought to assess the effect of short-term apolipoprotein (apo) A-
IMilano administration on plaque size and on suspected markers of plaque vulnerability …

Effects of reconstituted high-density lipoprotein infusions on coronary atherosclerosis: a randomized controlled trial

JC Tardif, J Grégoire, PL L'Allier, R Ibrahim… - Jama, 2007 - jamanetwork.com
ContextHigh-density lipoprotein (HDL) cholesterol is an inverse predictor of coronary
atherosclerotic disease. Preliminary data have suggested that HDL infusions can induce …

Arterial remodeling in the left coronary system: the role of high-density lipoprotein cholesterol

AJ Taylor, AP Burke, A Farb, P Yousefi… - Journal of the American …, 1999 - jacc.org
OBJECTIVES We sought to evaluate the plaque and patient variables related to arterial
remodeling responses of early, de novo atherosclerotic lesions involving the left coronary …

Recombinant apolipoprotein AI Milano reduces intimal thickening after balloon injury in hypercholesterolemic rabbits.

S Ameli, A Hultgardh-Nilsson, B Cercek, PK Shah… - Circulation, 1994 - Am Heart Assoc
BACKGROUND Several epidemiological studies have shown an inverse relation between
high-density lipoprotein (HDL) cholesterol levels and coronary heart disease. Recently …

Dose-Related Effects of Repeated ETC-216 (Recombinant Apolipoprotein AIMilano/1-Palmitoyl-2-Oleoyl Phosphatidylcholine Complexes) Administrations on Rabbit …

C Parolini, M Marchesi, P Lorenzon, M Castano… - Journal of the American …, 2008 - jacc.org
Objectives: This study sought to evaluate in vivo the minimal dose of apolipoprotein (apo) A-
IMilano phospholipid complex (recombinant apoA-IMilano and 1-palmitoyl-2-oleoyl …

Effect of infusion of high-density lipoprotein mimetic containing recombinant apolipoprotein AI Milano on coronary disease in patients with an acute coronary …

SJ Nicholls, R Puri, CM Ballantyne, JW Jukema… - JAMA …, 2018 - jamanetwork.com
Importance Infusing a high-density lipoprotein mimetic containing apolipoprotein AI Milano
demonstrated potential atheroma regression in patients following an acute coronary …

Modulation of lipoprotein (a) atherogenicity by high density lipoprotein cholesterol levels in middle-aged men with symptomatic coronary artery disease and normal to …

C Cobbaert, JW Jukema, AH Zwinderman… - Journal of the American …, 1997 - jacc.org
Objectives. This study sought to examine whether lipoprotein (a) levels predict coronary
artery lumen changes in patients with symptomatic coronary artery disease (CAD) and …

Paradoxical increase in lumen size during progression of coronary atherosclerosis: observations from the REVERSAL trial

I Sipahi, EM Tuzcu, P Schoenhagen, SJ Nicholls… - Atherosclerosis, 2006 - Elsevier
Relative changes in lumen size during progression and regression of coronary
atherosclerosis remain largely unknown. We assessed these changes using serial …

Compensatory enlargement of human coronary arteries during progression of atherosclerosis is unrelated to atheroma burden: serial intravascular ultrasound …

I Sipahi, EM Tuzcu, P Schoenhagen… - European heart …, 2006 - academic.oup.com
Aims On the basis of the evidence from autopsy studies, it is accepted that compensatory
enlargement (remodelling) of coronary arteries during progression of atherosclerosis …