Randomized controlled trial of rituximab and cost‐effectiveness analysis in treating fatigue and oral dryness in primary Sjögren's syndrome

SJ Bowman, CC Everett, JL O'Dwyer… - Arthritis & …, 2017 - Wiley Online Library
Objective To investigate whether rituximab, an anti–B cell therapy, improves symptoms of
fatigue and oral dryness in patients with primary Sjögren's syndrome (SS). Methods We …

Reduction of fatigue in Sjögren syndrome with rituximab: results of a randomised, double-blind, placebo-controlled pilot study

S Dass, SJ Bowman, EM Vital, K Ikeda… - Annals of the …, 2008 - ard.bmj.com
Objective: Primary Sjögren syndrome (pSS) causes significant systemic symptoms including
fatigue as well as glandular dysfunction. There are currently no effective systemic therapies; …

Effectiveness of rituximab treatment in primary Sjögren's syndrome: a randomized, double‐blind, placebo‐controlled trial

JM Meijer, PM Meiners, A Vissink… - Arthritis & …, 2010 - Wiley Online Library
Objective. To study the efficacy and safety of B cell depletion with rituximab, a chimeric
murine/human anti-CD20 monoclonal antibody, in patients with primary Sjögren's syndrome …

Treatment guidelines for rheumatologic manifestations of Sjögren's syndrome: use of biologic agents, management of fatigue, and inflammatory musculoskeletal pain

SE Carsons, FB Vivino, A Parke… - Arthritis care & …, 2017 - Wiley Online Library
Objective The Sjögren's Syndrome Foundation clinical practice guidelines (CPGs) are
designed to improve quality and consistency of care in Sjögren's syndrome by offering …

Treatment of primary Sjögren syndrome with rituximab: a randomized trial

V Devauchelle-Pensec, X Mariette… - Annals of internal …, 2014 - acpjournals.org
Background: Primary Sjögren syndrome (pSS) is an autoimmune disorder characterized by
ocular and oral dryness or systemic manifestations. Objective: To evaluate efficacy and …

Severe Health‐Related quality of life impairment in active primary Sjögren's syndrome and Patient‐Reported outcomes: data from a large therapeutic trial

D Cornec, V Devauchelle‐Pensec… - Arthritis Care & …, 2017 - Wiley Online Library
Objective To identify the principal determinants of health‐related quality of life (HRQOL)
impairment in patients with active primary Sjögren's syndrome (SS) participating in a large …

Rituximab therapy for primary Sjögren's syndrome: an open‐label clinical trial and mechanistic analysis

EW St. Clair, MC Levesque, ETL Prak… - Arthritis & …, 2013 - Wiley Online Library
Objective To study the safety and clinical efficacy of rituximab therapy for primary Sjögren's
syndrome, as well as to investigate its mechanisms. Methods Patients with primary Sjögren's …

Efficacy and safety of rituximab treatment in early primary Sjögren's syndrome: a prospective, multi-center, follow-up study

F Carubbi, P Cipriani, A Marrelli, PD Benedetto… - Arthritis research & …, 2013 - Springer
Abstract Introduction Primary Sjögren's syndrome (pSS) is an autoimmune disorder affecting
exocrine glands; however, a subgroup of pSS patients experience systemic extra-glandular …

Efficacy of rituximab in systemic manifestations of primary Sjögren's syndrome: results in 78 patients of the AutoImmune and Rituximab registry

JE Gottenberg, G Cinquetti, C Larroche… - Annals of the …, 2013 - ard.bmj.com
Objectives To evaluate the efficacy and safety of rituximab in patients with primary Sjögren's
syndrome (pSS). Methods The AutoImmune and Rituximab registry has included 86 patients …

Brief report: ultrasonographic assessment of salivary gland response to rituximab in primary Sjögren's syndrome

S Jousse‐Joulin, V Devauchelle‐Pensec… - Arthritis & …, 2015 - Wiley Online Library
Objective To evaluate changes in salivary gland echostructure and vascularization after
rituximab treatment in patients with primary Sjögren's syndrome (SS). Methods Twenty‐eight …