Increased prevalence of clonal hematopoiesis of indeterminate potential amongst people living with HIV

AG Bick, K Popadin, CW Thorball, MM Uddin… - Scientific reports, 2022 - nature.com
People living with human immunodeficiency virus (PLWH) have significantly increased risk
for cardiovascular disease in part due to inflammation and immune dysregulation. Clonal …

Risk factors for clonal hematopoiesis of indeterminate potential in people with HIV: a report from the REPRIEVE trial

R Bhattacharya, MM Uddin, AP Patel, A Niroula… - Blood …, 2024 - ashpublications.org
Clonal hematopoiesis of indeterminate potential (CHIP), the clonal expansion of myeloid
cells with leukemogenic mutations, results in increased coronary artery disease (CAD) risk …

Clonal hematopoiesis in men living with HIV and association with subclinical atherosclerosis

S Wang, S Pasca, WS Post, S Langan, A Pallavajjala… - Aids, 2022 - journals.lww.com
Objectives: People with HIV (PWH) are at increased risk for premature cardiovascular
disease (CVD). Clonal hematopoiesis is a common age-related condition that may be …

Clonal hematopoiesis and risk of atherosclerotic cardiovascular disease

S Jaiswal, P Natarajan, AJ Silver… - … England Journal of …, 2017 - Mass Medical Soc
Background Clonal hematopoiesis of indeterminate potential (CHIP), which is defined as the
presence of an expanded somatic blood-cell clone in persons without other hematologic …

Clonal hematopoiesis is associated with low CD4 nadir and increased residual HIV transcriptional activity in virally suppressed individuals with HIV

WA van der Heijden, RC van Deuren… - The Journal of …, 2022 - academic.oup.com
Clonal hematopoiesis, a common age-related phenomenon marked by expansion of cells
with clonal hematopoiesis driver mutations, has been associated with all-cause mortality …

Association of diet quality with prevalence of clonal hematopoiesis and adverse cardiovascular events

R Bhattacharya, SM Zekavat, MM Uddin… - JAMA …, 2021 - jamanetwork.com
Importance Clonal hematopoiesis of indeterminate potential (CHIP), the expansion of
somatic leukemogenic variations in hematopoietic stem cells, has been associated with …

Common and rare variant associations with clonal haematopoiesis phenotypes

MD Kessler, A Damask, S O'Keeffe, N Banerjee, D Li… - Nature, 2022 - nature.com
Clonal haematopoiesis involves the expansion of certain blood cell lineages and has been
associated with ageing and adverse health outcomes,,,–. Here we use exome sequence …

Clonal hematopoiesis of indeterminate potential predicts adverse outcomes in patients with atherosclerotic cardiovascular disease

ED Gumuser, A Schuermans, SMJ Cho… - Journal of the American …, 2023 - jacc.org
Background Clonal hematopoiesis of indeterminate potential (CHIP)—the age-related clonal
expansion of blood stem cells with leukemia-associated mutations—is a novel …

Exome sequencing of 628,388 individuals identifies common and rare variant associations with clonal hematopoiesis phenotypes

MD Kessler, A Damask, S O'Keeffe, M Van Meter… - MedRxiv, 2022 - medrxiv.org
Clonal hematopoiesis (CH) refers to the expansion of certain blood cell lineages and has
been associated with aging and adverse health outcomes. Here, we use exome sequence …

Human immunodeficiency virus and clonal hematopoiesis

SC Vorri, I Christodoulou, S Karanika, T Karantanos - Cells, 2023 - mdpi.com
The evolution of antiretroviral therapies (ART) has tremendously improved the life
expectancy of people living with human immunodeficiency virus (HIV)(PLWH), which is …