Abstract Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominant disorder. Lithium is
able to stimulate autophagy, and to reduce Ca 2+ efflux from the inositol-1, 4, 5-triphosphate …

Spinocerebellar ataxia type 3 (SCA3), also known as Machado–Joseph disease (MJD), is
an autosomal-dominant neurodegenerative disorder caused by a polyglutamine expansion …

Background Spinocerebellar ataxia type 1 (SCA1) is a dominantly inherited
neurodegenerative disorder characterized by progressive motor and cognitive dysfunction …

Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominantly inherited,
neurodegenerative disease caused by an expansion of polyglutamine tracts in the cytosolic …

Clinical phenotype of individuals with spinocerebellar ataxia 2 (SCA2) is characterised by
cerebellar ataxia and cognitive impairment. Although L-dopa-responsive Parkinsonism is …

OBJECTIVES: Cognitive disorders and dementia occur in 19 to 42% of patients with
spinocerebellar ataxia type 2 (SCA2). Neuropsychological tests can reveal executive …

Abstract Spinocerebellar ataxias type 1 (SCA1) is an autosomal dominant disease usually
manifesting in adulthood. We performed a prospective 1-year longitudinal study in 14 …

The clinical spectrum of spinocerebellar ataxia 3 (SCA 3) disease is wide and varied. We
describe a Chinese patient with a mutation at the SCA 3 locus with clinical features of …

Objective Spinocerebellar ataxia type 3 (SCA3) is an inherited neurodegenerative disorder
characterized by cerebellar ataxia and variable expression of clinical features beyond the …

Abstract Spinocerebellar ataxia type 2 (SCA2) and type 3 (SCA3) are autosomal-dominant
neurodegenerative disorders. SCA2 primarily affects cerebellar Purkinje neurons. SCA3 …