Analysis of active ricin and castor bean proteins in a ricin preparation, castor bean extract, and surface swabs from a public health investigation

DM Schieltz, SC McGrath, LG McWilliams… - Forensic science …, 2011 - Elsevier
In late February 2008, law enforcement officials in Las Vegas, Nevada, discovered in a hotel
room, a copy of The Anarchist Cookbook, suspected castor beans and a “white powder” …

Rapid and sensitive identification of ricin in environmental samples based on lactamyl agarose beads using LC‐MS/MS (MRM)

L Feldberg, O Schuster, E Elhanany… - Journal of mass …, 2020 - Wiley Online Library
Ricin, a plant‐derived toxin extracted from the seeds of Ricinus communis (castor bean
plant), is one of the most toxic proteins known. Ricin's high toxicity, widespread availability …

Ricin-like proteins from the castor plant do not influence liquid chromatography-mass spectrometry detection of ricin in forensically relevant samples

ED Merkley, SC Jenson, JS Arce, AM Melville… - Toxicon, 2017 - Elsevier
The toxic protein ricin (also known as RCA60), found in the seed of the castor plant (Ricinus
communis) is frequently encountered in law enforcement investigations. The ability to detect …

Forensic identification of neat ricin and of ricin from crude castor bean extracts by mass spectrometry

SÅ Fredriksson, AG Hulst, E Artursson… - Analytical …, 2005 - ACS Publications
The protein toxin ricin, which originates from the seeds of Ricinus communis plants, has
been the subject of increased interest, due to its potential terrorist use. Exceptionally, this …

[HTML][HTML] Recommended mass spectrometry-based strategies to identify ricin-containing samples

SR Kalb, DM Schieltz, F Becher, C Astot… - Toxins, 2015 - mdpi.com
Ricin is a protein toxin produced by the castor bean plant (Ricinus communis) together with
a related protein known as R. communis agglutinin (RCA120). Mass spectrometric (MS) …

Forensic determination of ricin and the alkaloid marker ricinine from castor bean extracts

SM Darby, ML Miller, RO Allen - Journal of …, 2001 - asmedigitalcollection.asme.org
Liquid chromatography/mass spectrometry (LC/MS) and matrix assisted laser
desorption/ionization time-of-flight (MALDI-TOF) MS methods were developed for the …

[HTML][HTML] Integration of gas chromatography mass spectrometry methods for differentiating ricin preparation methods

DS Wunschel, AM Melville, CJ Ehrhardt, HA Colburn… - Analyst, 2012 - pubs.rsc.org
The investigation of crimes involving chemical or biological agents is infrequent, but
presents unique analytical challenges. The protein toxin ricin is encountered more …

Analysis of carbohydrate and fatty acid marker abundance in ricin toxin preparations for forensic information

HA Colburn, DS Wunschel, HW Kreuzer… - Analytical …, 2010 - ACS Publications
One challenge in the forensic analysis of ricin samples is determining the method and extent
of sample preparation. Ricin purification from the source castor seeds is essentially a protein …

[HTML][HTML] Rapid, sensitive and reliable ricin identification in serum samples using LC–MS/MS

L Feldberg, E Elhanany, O Laskar, O Schuster - Toxins, 2021 - mdpi.com
Ricin, a protein derived from the seeds of the castor bean plant (Ricinus communis), is a
highly lethal toxin that inhibits protein synthesis, resulting in cell death. The widespread …

Development and validation of an ELISA kit for the detection of ricin toxins from biological specimens and environmental samples

HY Chen, H Tran, LY Foo, TW Sew… - Analytical and bioanalytical …, 2014 - Springer
Ricin is a toxin that can be easily extracted from seeds of Ricinus communis plants. Ricin is
considered to be a major bio-threat as it can be freely and easily acquired in large …