Objective Polycystic ovary syndrome (PCOS) is a multigenic disorder, and insulin resistance
is one of its hallmark features. Polymorphisms in exon 17 of insulin receptor (INSR) gene are …

Sažetak Obesity and insulin resistance is a common finding in patients with polycystic ovary
syndrome (PCOS). Significant number of PCOS women experience insulin resistance that is …

Polycystic ovary syndrome (PCOS) is the most common gynecological endocrine disorder.
The genetic background is believed to play a crucial role in the pathogenesis of PCOS. In …

The insulin receptor (INSR), which is an indispensable component of the insulin-signalling
pathway, could be a plausible candidate gene for polycystic ovary syndrome (PCOS). This …

To investigate the association of single-nucleotide polymorphisms (SNPs) in exon 17 of the
insulin receptor (INSR) gene with insulin resistance and INSR β-subunit expression in …

Polycystic ovarian syndrome (PCOS), a major cause of infertility, is also strongly associated
with insulin resistance. Defects in insulin receptor signaling are considered as one of the …

OBJECTIVE: To examine whether the insulin receptor (INSR) gene contributes to genetic
susceptibility to the polycystic ovary syndrome (PCOS). DESIGN: Case–control study …

Polycystic ovary syndrome (PCOS) is a heterogeneous condition with unknown aetiology
which is considered to be the most common endocrine disorder in women of reproductive …

Insulin resistance is one of the main characteristics of polycystic ovary syndrome (PCOS)
and is probably genetically predisposed. Possible associations of variable nucleotide …

Background Insulin resistance and glucose dysmetabolism in polycystic ovary syndrome
(PCOS) are related with the polymorphisms in the genes encoding the insulin receptor …