Early detection is an effective means of reducing cancer mortality. Here, we describe a
highly sensitive high-throughput screen that can identify panels of markers for the early …

Purpose: We undertook a systematic approach to identify breast cancer (BC) marker genes
with molecular assays and evaluated these marker genes for the detection of minimal …

Several methods have been used recently to determine gene expression profiles of cell
populations. Here we demonstrate the strength of combining two approaches, serial …

Blood-borne distant metastasis is the leading cause of cancer-related death in breast
cancer. The onset of this fundamental process can now be assessed in cancer patients …

This study was initiated to identify biomarkers with potential value for the early detection of
poor-outcome breast cancer. Two sets of well-characterized tissues were utilized: one from …

Introduction Existing methods to detect breast cancer in asymptomatic patients have
limitations, and there is a need to develop more accurate and convenient methods. In this …

BACKGROUND Molecular characterization of circulating tumor cells (CTCs) is crucial to
identify novel diagnostic and therapeutic targets for individualized therapies. We developed …

Expression profiles of breast carcinomas are difficult to interpret when they are obtained
from tissue in toto, which may contain a large proportion of non-cancer cells. To avoid this …

Purpose: The goal of this study was to develop a molecular diagnostic assay to detect
circulating breast cancer cells in the peripheral blood for the purpose of staging breast …

Introduction Early detection of breast cancer is key to successful treatment and patient
survival. We have previously reported the potential use of gene expression profiling of …