Dysregulation of circulating miRNAs promotes the pathogenesis of diabetes-induced cardiomyopathy
Diabetic Cardiomyopathy (DCM) is characterized by myocardial dysfunction caused by
diabetes mellitus. After-effects of diabetic cardiomyopathy are far more lethal than non …
diabetes mellitus. After-effects of diabetic cardiomyopathy are far more lethal than non …
Investigating microRNAs in diabetic cardiomyopathy as tools for early detection and therapeutics
P Mathur, V Rani - Molecular and Cellular Biochemistry, 2023 - Springer
To profile microRNAs population of glucose-induced cardiomyoblast cell line and identify
the differentially expressed microRNAs and their role under pre-diabetes and diabetes …
the differentially expressed microRNAs and their role under pre-diabetes and diabetes …
Pathogenesis of Diabetic Cardiomyopathy and role of miRNA
Diabetic cardiomyopathy is characterized as abnormal function and structure of myocardium
associated with diabetes irrespective of other cardiac risk factors like hypertension or …
associated with diabetes irrespective of other cardiac risk factors like hypertension or …
MicroRNA targets and biomarker validation for diabetes-associated cardiac fibrosis
ZQ Jin - Pharmacological research, 2021 - Elsevier
Cardiac fibrosis is one of the main characteristics of diabetic cardiomyopathy and manifests
excessive accumulation of extracellular matrix proteins in the heart. Several signaling …
excessive accumulation of extracellular matrix proteins in the heart. Several signaling …
MicroRNAs: A critical regulator and a promising therapeutic and diagnostic molecule for diabetic cardiomyopathy
P Mathur, V Rani - Current Gene Therapy, 2021 - ingentaconnect.com
The risk of heart failure is 2-5 times higher in diabetic patients as compared to non-diabetic
patients with similar comorbidities. Recent reports suggest that nearly half of the diabetic …
patients with similar comorbidities. Recent reports suggest that nearly half of the diabetic …
Cardiac miRNA expression and their mRNA targets in a rat model of prediabetes
Little is known about the mechanism of prediabetes-induced cardiac dysfunction. Therefore,
we aimed to explore key molecular changes with transcriptomic and bioinformatics …
we aimed to explore key molecular changes with transcriptomic and bioinformatics …
The role of microRNAs in the pathophysiology, diagnosis, and treatment of diabetic cardiomyopathy
M Abdel Rhman, P Owira - Journal of Pharmacy and …, 2022 - academic.oup.com
Introduction Diabetic cardiomyopathy (DCM) is an end-point macrovascular complication
associated with increased morbidity and mortality in 12% of diabetic patients. MicroRNAs …
associated with increased morbidity and mortality in 12% of diabetic patients. MicroRNAs …
Differentially expressed microRNAs and their target genes in the hearts of streptozotocin-induced diabetic mice
X Diao, E Shen, X Wang, B Hu - Molecular medicine …, 2011 - spandidos-publications.com
Persistent hyperglycemia in diabetic patients has been associated with cardiac hypertrophy,
myocardial fibrosis and cardiac dysfunction. However, the underlying mechanisms of this …
myocardial fibrosis and cardiac dysfunction. However, the underlying mechanisms of this …
Recent highlights of research on miRNAs as early potential biomarkers for cardiovascular complications of type 2 diabetes mellitus
A Bielska, M Niemira, A Kretowski - International Journal of Molecular …, 2021 - mdpi.com
Type 2 diabetes mellitus (T2DM) and its complications pose a serious threat to the life and
health of patients around the world. The most dangerous complications of this disease are …
health of patients around the world. The most dangerous complications of this disease are …
Serum miRNA profile in diabetic patients with ischemic heart disease as a promising non-invasive biomarker
A Bielska, M Niemira, W Bauer, I Sidorkiewicz… - Frontiers in …, 2022 - frontiersin.org
The increasing morbidity and mortality of type 2 diabetic mellitus (T2DM) patients with
ischemic heart disease (IHD) highlight an urgent need to identify early biomarkers, which …
ischemic heart disease (IHD) highlight an urgent need to identify early biomarkers, which …