Mucosal vaccine design and delivery

KA Woodrow, KM Bennett, DD Lo - Annual review of biomedical …, 2012 - annualreviews.org
Mucosal surfaces are a major portal of entry for many human pathogens that are the cause
of infectious diseases worldwide. Vaccines capable of eliciting mucosal immune responses …

Mucosal vaccines: Strategies and challenges

M Li, Y Wang, Y Sun, H Cui, SJ Zhu, HJ Qiu - Immunology letters, 2020 - Elsevier
Mucosal immunization has potential benefits over conventional parenteral immunization,
eliciting immune defense in both mucosal and systemic tissue for protecting from pathogen …

Mucosal vaccines: a paradigm shift in the development of mucosal adjuvants and delivery vehicles

A Srivastava, DV Gowda, SRV Madhunapantula… - Apmis, 2015 - Wiley Online Library
Mucosal immune responses are the first‐line defensive mechanisms against a variety of
infections. Therefore, immunizations of mucosal surfaces from which majority of infectious …

Defending the mucosa: adjuvant and carrier formulations for mucosal immunity

LB Lawson, EB Norton, JD Clements - Current opinion in immunology, 2011 - Elsevier
A majority of infectious microorganisms either colonize or cross mucosal surfaces to enter
the host. A major goal in vaccine design is to induce a protective, lasting immune response …

New insights in mucosal vaccine development

V Pavot, N Rochereau, C Genin, B Verrier, S Paul - Vaccine, 2012 - Elsevier
Mucosal surfaces are the major entrance for infectious pathogens and therefore mucosal
immune responses serve as a first line of defence. Most current immunization procedures …

Current and new approaches for mucosal vaccine delivery

JH Rhee - Mucosal vaccines, 2020 - Elsevier
Mucosal surfaces are the interface between the host's internal milieu and the external
environment, and they have dual functions, serving as physical barriers to foreign antigens …

Recent advances in mucosal vaccine development

H Chen - Journal of controlled release, 2000 - Elsevier
Proper stimulation of the mucosal immune system is critical for the effective protection of
mucosal surfaces against colonization and invasion of infectious agents. This requires …

The development of mucosal vaccines for both mucosal and systemic immune induction and the roles played by adjuvants

SH Kim, YS Jang - Clinical and experimental vaccine …, 2017 - synapse.koreamed.org
Vaccination is the most successful immunological practice that improves the quality of
human life and health. Vaccine materials include antigens of pathogens and adjuvants …

Mucosal vaccines: recent progress in understanding the natural barriers

O Borges, F Lebre, D Bento, G Borchard… - Pharmaceutical …, 2010 - Springer
It has long been known that protection against pathogens invading the organism via
mucosal surfaces correlates better with the presence of specific antibodies in local …

Challenges in mucosal vaccines for the control of infectious diseases

T Azegami, Y Yuki, H Kiyono - International immunology, 2014 - academic.oup.com
The mucosal surface is the largest route through which pathogens enter the human body. To
control the outbreak of mucosal infectious diseases, we must use our knowledge of the …