Understanding the signals that guide neuronal development and direct formation of axons,
dendrites, and synapses during wiring of the brain is a fundamental challenge in …

Communication between different brain regions, and between local circuits in the same
brain region, is an important area of study for basic and translational neuroscience research …

Embryogenesis is a highly regulated process in which the precise spatial and temporal
release of soluble cues directs differentiation of multipotent stem cells into discrete …

The brain is the most intricate, energetically active, and plastic organ in the body. These
features extend to its cellular elements, the neurons and glia. Understanding neurons, or …

Various experimental models are used to study brain development and degeneration. They
range from whole animal models, which preserve anatomical structures but strongly limit …

Microfabrication processes have changed the technology used in consumer goods, and
have now advanced into applications in biology. Microfluidic platforms are microfabricated …

Neurotransmitters and neuromodulators are molecules within the nervous system that play
key roles in cell-to-cell communication. Upon stimulation, neurons release these signaling …

The widespread adoption of microfluidic devices among the neuroscience and neurobiology
communities has enabled addressing a broad range of questions at the molecular, cellular …

Methods to compartmentalize neurons allow distinct neuronal segments (ie, cell bodies,
axons, dendrites, or synapses) to be accessed, visualized, and/or manipulated …

Recently, microfluidic systems have shown great potential in the study of molecular and
cellular biology. With its excellent properties, such as miniaturization, integration and …